{"id":"W2047832591","doi":"10.1111/j.1365-2249.2006.03080.x","title":"Maturation of dendritic cells by necrotic thyrocytes facilitates induction of experimental autoimmune thyroiditis","year":2006,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Thyroglobulin; Autoimmune thyroiditis; Thyroiditis; Immunology; Dendritic cell; Autoimmunity; T cell; Antigen presentation; MHC class II; Thyroid; Biology; Antigen; Immune system; Medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004073046,0.0004108452,0.001024075,0.0001822834,0.0002149022,0.00001646625,0.0004756005,0.0007165151,0.001168007],"category_scores_gemma":[0.00009063888,0.0003940987,0.0004408249,0.0002079731,0.002192392,0.0003007752,0.0001826802,0.000512531,0.0002317943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000097196,"about_ca_system_score_gemma":0.00008547158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006846142,"about_ca_topic_score_gemma":0.000002076001,"domain_scores_codex":[0.9959124,0.0009775871,0.001945515,0.0005321333,0.00009317559,0.0005392377],"domain_scores_gemma":[0.9978514,0.0007058172,0.0007036019,0.0005947145,0.0001243101,0.00002014686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002400346,0.002509397,0.0003014387,0.00001327822,0.0003620028,0.000002658341,0.000468858,0.000003008643,0.9897407,0.0007922815,0.002423995,0.0009820722],"study_design_scores_gemma":[0.004033795,0.002963506,0.009529688,0.00005405719,0.0000405571,0.00006608941,0.002677301,0.000003001614,0.9749479,0.0001017877,0.00524524,0.0003370526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8475927,0.1492239,0.00005842307,0.00006559536,0.002167971,0.0004223363,0.00008356361,0.00008139626,0.0003041703],"genre_scores_gemma":[0.9967993,0.000650839,0.0001693217,0.00005901744,0.00003919788,0.00007496102,0.0003980226,0.00004260196,0.001766736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1492066,"threshold_uncertainty_score":0.9998511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01807465240592089,"score_gpt":0.2992533932218964,"score_spread":0.2811787408159755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}