{"id":"W2047837196","doi":"10.1074/jbc.m111.306191","title":"NLRP7, a Nucleotide Oligomerization Domain-like Receptor Protein, Is Required for Normal Cytokine Secretion and Co-localizes with Golgi and the Microtubule-organizing Center","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Gestational Trophoblastic Disease Studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Pyrin domain; Biology; Secretion; Cell biology; Peripheral blood mononuclear cell; Golgi apparatus; Cytokine; Inflammasome; Immunology; Inflammation; Genetics; Endocrinology; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009022678,0.0003212546,0.0002198253,0.0001819676,0.0001927618,0.0003150342,0.0001578931,0.0003132659,0.0008149294],"category_scores_gemma":[0.0003264756,0.0001329222,0.0001937831,0.0001099905,0.0002511183,0.0001403414,0.0002370679,0.0002424426,0.0004355616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002001069,"about_ca_system_score_gemma":0.0001607197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002292932,"about_ca_topic_score_gemma":0.0001925847,"domain_scores_codex":[0.9998093,0.00004693945,0.00002207717,0.00003494444,0.00005462548,0.00003215376],"domain_scores_gemma":[0.9998093,0.00002585419,0.00007908636,0.00001837485,0.0000238155,0.00004345763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001123305,0.00001263462,0.001786095,0.00004673961,0.00001162713,0.001006109,0.00003701028,0.00006674867,0.9940196,0.0001317431,0.00007806822,0.002691306],"study_design_scores_gemma":[0.00004753809,0.0004143187,0.04625849,0.00003314987,0.00004620188,0.02079003,0.0002209156,0.001951014,0.9190165,0.0003831627,0.01082566,0.00001291696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942188,0.001985977,0.002428567,0.000145565,0.00002413413,0.00001057861,0.0002054464,0.0001065461,0.0008742847],"genre_scores_gemma":[0.9974868,0.0004858722,0.001034972,0.00002239599,0.000006673108,0.00001039459,0.0003154637,0.00001225979,0.0006251137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008149294,"threshold_uncertainty_score":0.002726138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0198652395346369,"score_gpt":0.2363376136080406,"score_spread":0.2164723740734038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}