{"id":"W2047861227","doi":"10.1073/pnas.0712064105","title":"Molecular basis for LDL receptor recognition by PCSK9","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":414,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; University of Chicago; Canadian Institutes of Health Research; Welch Foundation; Howard Hughes Medical Institute; Argonne National Laboratory; Foundation for the National Institutes of Health","keywords":"Kexin; PCSK9; LDL receptor; Proprotein convertase; Subtilisin; C2 domain; EGF-like domain; Receptor; Epidermal growth factor; Chemistry; Binding domain; Binding site; Biochemistry; Cell biology; Biology; Lipoprotein; Cholesterol; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05316344642461898,"score_gpt":0.3039674863607629,"score_spread":0.2508040399361439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}