{"id":"W2047907548","doi":"10.1182/blood-2002-04-1244","title":"Oncogenic interaction between BCR-ABL andNUP98-HOXA9 demonstrated by the use of an in vitro purging culture system","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Cancer research; Myeloid leukemia; Bone marrow; Leukemia; Chronic myelogenous leukemia; ABL; Biology; Philadelphia chromosome; Immunology; Stem cell; K562 cells; breakpoint cluster region; Medicine; Tyrosine kinase; Chromosomal translocation; Cell biology; Signal transduction; Receptor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001100599,0.0001636958,0.0003315261,0.00007445389,0.00005284474,0.00002508155,0.00009436646,0.0001295992,0.00004707131],"category_scores_gemma":[0.00004847088,0.0001124096,0.00007515815,0.0002718737,0.00004088967,0.0002052131,0.00002431052,0.0002826618,0.00002993464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004031782,"about_ca_system_score_gemma":0.00005174005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004242787,"about_ca_topic_score_gemma":0.00002257694,"domain_scores_codex":[0.9988372,0.0001224149,0.0003512807,0.0002421423,0.0002196168,0.0002273644],"domain_scores_gemma":[0.9992543,0.00009157536,0.0001519187,0.0003600445,0.00004783686,0.00009431641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005504742,0.004217436,0.1757688,0.0006680544,0.001866472,0.0004805,0.003792846,0.00006336395,0.7667993,0.00001646287,0.005038984,0.04073729],"study_design_scores_gemma":[0.03619515,0.001252088,0.02434255,0.00158789,0.003041997,0.001535102,0.003026544,0.01178946,0.9053739,0.000005662733,0.01123099,0.0006186824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981631,0.0005873745,0.00001344963,0.00009697732,0.0000543591,0.0004668954,0.00004908288,0.00006791725,0.0005008203],"genre_scores_gemma":[0.998815,0.00004194094,0.000391489,0.00003648112,0.000102759,0.00002198018,0.0001295696,0.00002158442,0.000439201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1514263,"threshold_uncertainty_score":0.4583929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03926552683287885,"score_gpt":0.2641455768159855,"score_spread":0.2248800499831067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}