{"id":"W2047932460","doi":"10.1210/en.2007-0157","title":"Type 1 Parathyroid Hormone Receptor (PTH1R) Nuclear Trafficking: Regulation of PTH1R Nuclear-Cytoplasmic Shuttling by Importin-α/β and Chromosomal Region Maintenance 1/Exportin 1","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Lawson Health Research Institute","keywords":"Importin; Nuclear transport; Cytoplasm; Nuclear export signal; Nuclear localization sequence; Cell nucleus; Cell biology; Biology; Nucleoporin; Molecular biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001453782,0.0002948908,0.0002554534,0.0001485024,0.000197903,0.0003956259,0.0002494044,0.0002379574,0.001371863],"category_scores_gemma":[0.00009593897,0.0001643457,0.0002700496,0.0001528807,0.0002668875,0.0002902311,0.0002250607,0.0004579198,0.0004299851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005342967,"about_ca_system_score_gemma":0.0002183313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009152517,"about_ca_topic_score_gemma":0.001311738,"domain_scores_codex":[0.9998782,0.00001591236,0.000008713455,0.00004115028,0.00002825109,0.00002777583],"domain_scores_gemma":[0.9999355,0.000008383996,0.00002581027,0.000003568534,0.000008775584,0.0000178985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001185387,0.00001317455,0.0001329705,0.0000633422,0.000003277423,0.00005299975,0.00002122649,0.0000376829,0.9980766,0.0001103463,0.00008824371,0.001281626],"study_design_scores_gemma":[0.00007444465,0.0001718967,0.01820317,0.00001873896,0.00003160424,0.000657575,0.0001038898,0.002441465,0.9701537,0.0001199768,0.008009643,0.00001385695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718916,0.01759782,0.006156547,0.0005706776,0.0000899554,0.00004708732,0.0005242331,0.000279907,0.002842296],"genre_scores_gemma":[0.9850312,0.006016538,0.00313918,0.0001351898,0.00003046006,0.00006024085,0.0006366724,0.00005539389,0.004895198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001371863,"threshold_uncertainty_score":0.004589319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006808461588206497,"score_gpt":0.2159108826848872,"score_spread":0.2091024210966807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}