{"id":"W2047956375","doi":"10.1053/j.gastro.2009.06.055","title":"Analysis of the Gene Coding for the BRCA2-Interacting Protein PALB2 in Familial and Sporadic Pancreatic Cancer","year":2009,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; Mount Sinai Hospital; McGill University Health Centre; Centre Hospitalier de l’Université de Montréal; McGill University; Jewish General Hospital","funders":"National Cancer Institute; National Institutes of Health; Jewish General Hospital; Lustgarten Foundation; Susan G. Komen for the Cure","keywords":"PALB2; Pancreatic cancer; Medicine; Cancer research; Gene; Genetics; Oncology; Cancer; Internal medicine; Biology; Mutation; Germline mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004728362,0.0005635915,0.0008390229,0.0007252493,0.00105898,0.0006728676,0.0007177811,0.009976479,0.001738643],"category_scores_gemma":[0.004220639,0.0003413495,0.0008032194,0.0004838624,0.001040953,0.000704645,0.0004342112,0.00379599,0.0006902096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001275682,"about_ca_system_score_gemma":0.0004128633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002702101,"about_ca_topic_score_gemma":0.002011519,"domain_scores_codex":[0.9995174,0.0001129318,0.00006468353,0.000101119,0.0001026512,0.0001011395],"domain_scores_gemma":[0.9984181,0.0009907803,0.00009683414,0.00007702971,0.0001624898,0.0002547848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.00084594,0.000131857,0.03922851,0.00009370285,0.0000876479,0.9027489,0.0004974536,0.0004246119,0.008728542,0.001888349,0.03518597,0.01013855],"study_design_scores_gemma":[0.0004359568,0.0006435476,0.04854673,0.0001483622,0.0002681501,0.8934439,0.0009329881,0.006475694,0.007223535,0.004296158,0.03750905,0.00007591747],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6618171,0.005008088,0.002168301,0.3010618,0.009153047,0.0001036583,0.0004958244,0.0001458263,0.02004626],"genre_scores_gemma":[0.9359292,0.001581521,0.001133434,0.04619316,0.008400899,0.00003536775,0.0001550371,0.00004774207,0.006523742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009976479,"threshold_uncertainty_score":0.009255826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03126990609588832,"score_gpt":0.3285153721064252,"score_spread":0.2972454660105369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}