{"id":"W2047964782","doi":"10.1517/17460441.3.11.1267","title":"Scintillation proximity assay in lead discovery","year":2008,"lang":"en","type":"article","venue":"Expert Opinion on Drug Discovery","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Drug discovery; Lead (geology); Computational biology; Scintillation; Biology; Computer science; Bioinformatics; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802655,0.0002444003,0.0001978543,0.0001080633,0.0001162171,0.00004746052,0.0002331099,0.0001473378,0.000007191511],"category_scores_gemma":[0.0001260131,0.0002281414,0.0001052412,0.0001541804,0.0001800051,0.0001071414,0.0001360289,0.0001702526,0.00001437352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008557717,"about_ca_system_score_gemma":0.0001050708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005693258,"about_ca_topic_score_gemma":0.00002638542,"domain_scores_codex":[0.9984736,0.0001060066,0.0002874418,0.0005908713,0.0002240451,0.0003179953],"domain_scores_gemma":[0.999288,0.00002301587,0.000100108,0.000506249,0.00003527279,0.00004737449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004140761,0.0003830562,0.0174605,0.00001383799,0.00001551732,0.00001114014,0.000310252,0.0004045175,0.9522107,0.0004604097,0.02541008,0.002905913],"study_design_scores_gemma":[0.0005416946,0.0001814214,0.006883622,0.0001134156,5.349098e-7,0.00001595622,0.0001051623,0.0001262954,0.9552345,0.000126072,0.03624963,0.0004216381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9534697,0.003259376,0.03895915,0.0006828732,0.0009418221,0.000757227,0.00004116512,0.0001069789,0.00178172],"genre_scores_gemma":[0.9894127,0.004267393,0.003319497,0.0005802183,0.0003882895,0.00008469564,0.0001610494,0.00004373888,0.001742475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03594296,"threshold_uncertainty_score":0.9303337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01726821812723654,"score_gpt":0.3028765617550481,"score_spread":0.2856083436278115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}