{"id":"W2047979269","doi":"10.1021/jm990441x","title":"Design and Solution Structure of Functional Peptide Mimetics of Nerve Growth Factor","year":2000,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute","funders":"","keywords":"Chemistry; Tropomyosin receptor kinase A; Nerve growth factor; Peptide; Receptor; Stereochemistry; Biophysics; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001600991,0.0002982273,0.0002518386,0.0001138148,0.0001354696,0.0002479321,0.0003671084,0.0002741696,0.0008978088],"category_scores_gemma":[0.0002436941,0.0001563368,0.0001897411,0.0001393549,0.0001386468,0.0001974343,0.0001535854,0.0004896024,0.0002907291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003795479,"about_ca_system_score_gemma":0.0001978179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002079937,"about_ca_topic_score_gemma":0.0002334326,"domain_scores_codex":[0.9999256,0.00001914344,0.000007700426,0.00001458681,0.00001934243,0.00001360589],"domain_scores_gemma":[0.999935,0.0000138487,0.0000203195,0.000003677343,0.000009734659,0.00001737245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004614515,0.0001882801,0.0001556143,0.0001421812,0.00001591474,0.0001466208,0.00004185057,0.008233401,0.9833843,0.001162476,0.0001655548,0.005902348],"study_design_scores_gemma":[0.0003353967,0.002773472,0.0005195873,0.00002289161,0.00004833396,0.0002083004,0.000050697,0.0205401,0.9667426,0.0003989142,0.008340758,0.00001906663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988695,0.001429276,0.007697463,0.0001176873,0.00004321768,0.0001726755,0.0001748219,0.00005343719,0.001616386],"genre_scores_gemma":[0.9787785,0.00133436,0.01762529,0.0000955908,0.00002090823,0.000148743,0.0005108236,0.00001917286,0.001466642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008978088,"threshold_uncertainty_score":0.003003418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02630140413361905,"score_gpt":0.245519370454622,"score_spread":0.219217966321003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}