{"id":"W2047985957","doi":"10.1016/j.tiv.2004.01.005","title":"Morphine-promoted survival of CEM×174 cells in early stages of SIV infection in vitro: involvement of the multiple molecular mechanisms","year":2004,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Peking University; Chinese Academy of Medical Sciences; National Natural Science Foundation of China; University of Chinese Academy of Sciences; Academy of Medical Sciences","keywords":"Flow cytometry; MAPK/ERK pathway; Morphine; Immune system; Kinase; Intracellular; Phosphorylation; Calcium in biology; In vitro; Simian immunodeficiency virus; Blot; Apoptosis; Pharmacology; Biology; Cell cycle; Immunology; Chemistry; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008183298,0.0003244634,0.000281804,0.0001228438,0.0002302903,0.0002621858,0.0001956344,0.0001694518,0.001847065],"category_scores_gemma":[0.0001072238,0.0001118974,0.0002786079,0.00008651087,0.0001611865,0.0002156585,0.0002046774,0.0005916277,0.0002742726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001968658,"about_ca_system_score_gemma":0.0002483125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009536526,"about_ca_topic_score_gemma":0.001444066,"domain_scores_codex":[0.9999063,0.0000163773,0.000007000786,0.00001015123,0.00001775348,0.00004235714],"domain_scores_gemma":[0.999927,0.00001551513,0.00001271427,0.00001390722,0.00001303421,0.00001778218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007034885,0.00008390202,0.0005316889,0.00006041997,0.000006153381,0.00007326172,0.00004784967,0.00005219899,0.9954411,0.0002083766,0.00004729947,0.002744282],"study_design_scores_gemma":[0.00001473338,0.001102387,0.01300942,0.00001364199,0.00001321959,0.0001668946,0.00007462902,0.0002725948,0.9835131,0.00005219021,0.001760846,0.000006321706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959508,0.001884123,0.0008518151,0.00008585353,0.00003549353,0.00001881852,0.0003024022,0.00002180614,0.000848824],"genre_scores_gemma":[0.9955552,0.0009360918,0.000812708,0.00002000268,0.00001043714,0.00002813163,0.0002974223,0.000005995405,0.002333902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001847065,"threshold_uncertainty_score":0.006179035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01427981336244517,"score_gpt":0.2485584349512466,"score_spread":0.2342786215888014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}