{"id":"W2048099772","doi":"10.1038/sj.onc.1207475","title":"Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization","year":2004,"lang":"en","type":"article","venue":"Oncogene","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"National Cancer Institute; Neurosurgical Research Foundation; Pediatric Brain Tumor Foundation","keywords":"Biology; Molecular biology; Medulloblastoma; Suppression subtractive hybridization; HES1; Differential display; Gene; cDNA library; Cerebellum; Complementary DNA; Cancer research; Genetics; Downregulation and upregulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275368,0.0001018617,0.0001171129,0.00007371064,0.0000547295,0.00001132839,0.00005852159,0.00008659407,0.000002363431],"category_scores_gemma":[0.0000468043,0.0001051002,0.00002244925,0.00009781891,0.00004527347,0.000008047184,0.00005611228,0.00002870568,5.594844e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003589857,"about_ca_system_score_gemma":0.00007467881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000028558,"about_ca_topic_score_gemma":0.00006559253,"domain_scores_codex":[0.9991995,0.00004005055,0.0002965978,0.0002402149,0.0001128426,0.0001108361],"domain_scores_gemma":[0.999609,0.000004961238,0.0001475068,0.0001261227,0.00008444548,0.00002796385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006567599,0.00006299745,0.002444492,0.00002499237,0.00002113399,0.000001636454,0.0001233949,0.002081334,0.9934035,0.000005175002,0.000003013115,0.001762652],"study_design_scores_gemma":[0.000636894,0.00004545936,0.01663981,0.00005302275,0.00001332839,0.000008398863,0.00006652837,0.0001957143,0.9821308,0.00005202399,0.00005227166,0.0001057878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899109,0.0004684105,0.009330738,0.00002327291,0.00009959633,0.0001384766,0.000009374016,0.00000813731,0.00001108954],"genre_scores_gemma":[0.9981294,0.0002152465,0.001471814,0.000008014959,0.00003714562,0.00000775006,0.00009360105,0.00001487946,0.00002210425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01419532,"threshold_uncertainty_score":0.428586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01452073531495479,"score_gpt":0.2584474805438078,"score_spread":0.243926745228853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}