{"id":"W2048115478","doi":"10.1111/j.1365-2141.2004.05105.x","title":"Tetramolecular immune complexes are more efficient than IVIg to prevent antibody‐dependent <i>in vitro</i> and <i>in vivo</i> phagocytosis of blood cells","year":2004,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Héma-Québec","funders":"Canadian Institutes of Health Research; Bayer Canada","keywords":"Phagocytosis; In vivo; Opsonin; In vitro; Antibody; Immune system; Thrombocytopenic purpura; Immunology; Monoclonal antibody; Platelet; Immunoglobulin G; Pharmacology; Medicine; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003942528,0.0005170056,0.0006334432,0.0004130477,0.0001110366,0.0005326954,0.0003076753,0.0007726711,0.001977193],"category_scores_gemma":[0.0004199509,0.0001910158,0.0004170958,0.0002546046,0.0001993471,0.0003194496,0.0001381185,0.0009379229,0.0005114553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003603617,"about_ca_system_score_gemma":0.0002105144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005429348,"about_ca_topic_score_gemma":0.0004532849,"domain_scores_codex":[0.9995549,0.0001218489,0.00005652539,0.00006510644,0.0001072955,0.00009433821],"domain_scores_gemma":[0.9995219,0.0001024619,0.0001486753,0.00006160951,0.00006307885,0.0001023738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000557642,0.0002554478,0.0002183282,0.0001078981,0.00003805205,0.00003481402,0.00002070313,0.0001291113,0.9931147,0.000121649,0.0001875934,0.005214119],"study_design_scores_gemma":[0.0001194135,0.00412533,0.003028197,0.00001157145,0.00006591748,0.0002535333,0.00001020137,0.0004486041,0.9879518,0.00003003761,0.00394916,0.000006191036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786064,0.01316697,0.004813082,0.000185884,0.0001577276,0.000123458,0.0002442384,0.0001447265,0.002557622],"genre_scores_gemma":[0.987956,0.002576536,0.00360499,0.0002106449,0.0000936172,0.00007464654,0.00102687,0.00005026983,0.004406326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001977193,"threshold_uncertainty_score":0.006614387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005985135252188746,"score_gpt":0.2504104959760597,"score_spread":0.2444253607238709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}