{"id":"W2048140742","doi":"10.1089/clo.2006.8.189","title":"Human Embryonic Stem Cell–Derived Cells Rescue Visual Function in Dystrophic RCS Rats","year":2006,"lang":"en","type":"article","venue":"Cloning and Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":407,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Oklahoma","keywords":"Somatic cell nuclear transfer; Embryonic stem cell; Retinal pigment epithelium; Biology; Retinal; Stem cell; Retinal degeneration; Macular degeneration; Somatic cell; Retina; Cell biology; Transplantation; Epithelium; Cell culture; Pathology; Embryo; Ophthalmology; Medicine; Genetics; Neuroscience; Embryogenesis; Internal medicine; Blastocyst; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001740993,0.0002033929,0.0001836013,0.00007189193,0.0001556715,0.00006031619,0.00009094468,0.0001831082,0.000007895978],"category_scores_gemma":[6.331235e-7,0.0002005657,0.00005955544,0.00009988187,0.00005589437,0.00000627805,0.00006688719,0.0001200862,0.00001656095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001845259,"about_ca_system_score_gemma":0.0000456796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005995687,"about_ca_topic_score_gemma":0.00007224762,"domain_scores_codex":[0.9988024,0.00008210975,0.0002634538,0.0004187959,0.000117064,0.0003162078],"domain_scores_gemma":[0.9996595,0.000008633409,0.00007888348,0.000157173,0.00003424628,0.00006152987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006711212,0.00005456117,0.00280131,0.00005359689,0.00000923919,0.000009519993,0.00004643569,0.000386595,0.9949732,0.00002333051,0.0009593308,0.0006157522],"study_design_scores_gemma":[0.001010287,0.0004045731,0.009775823,0.00004716415,0.00001891971,0.000003444711,0.0004326778,0.0001378868,0.9827026,0.00002765138,0.005078934,0.0003600206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955946,0.00142987,0.000152637,0.0000240153,0.0002225148,0.0001662817,0.000002388216,0.00001925402,0.002388447],"genre_scores_gemma":[0.9901712,0.0001250734,0.00005685714,0.00004472139,0.0001072212,0.00001278959,0.00004680011,0.00002479687,0.009410524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0122706,"threshold_uncertainty_score":0.8178833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006230815854681613,"score_gpt":0.2121438801380122,"score_spread":0.2059130642833306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}