{"id":"W2048141918","doi":"10.1038/nsmb.1685","title":"Structural insight into mammalian sialyltransferases","year":2009,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences; University of British Columbia","funders":"","keywords":"Glycoconjugate; Glycolipid; Sialyltransferase; Immunogenicity; Glycoprotein; Biochemistry; Sialic acid; Glycobiology; Glycan; Enzyme; Cell biology; Cell adhesion; Chemistry; Computational biology; Biology; Cell; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001073586,0.0003910796,0.000300917,0.0001594243,0.0002195826,0.0000568249,0.0005285534,0.0009836098,0.0001831645],"category_scores_gemma":[0.0001960826,0.0003195248,0.0002266992,0.0002848307,0.0002014096,0.00001062713,0.00009471158,0.000693295,0.00001665911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003294879,"about_ca_system_score_gemma":0.0001025517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004232091,"about_ca_topic_score_gemma":0.00005329226,"domain_scores_codex":[0.9978637,0.0002101695,0.0003238031,0.0007591387,0.0002490976,0.0005941371],"domain_scores_gemma":[0.9989017,0.000009182608,0.00007514538,0.0005768182,0.0002197347,0.0002173959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002202265,0.000007806087,0.0006362358,0.000009289035,0.00004686969,0.00003366507,0.00004768432,0.00003596324,0.9728116,0.009759971,0.0002738913,0.01611678],"study_design_scores_gemma":[0.001262662,0.001125116,0.01422099,0.000008635242,0.00002199537,0.0001497817,0.00001803509,0.0001131268,0.9359322,0.009689248,0.03684156,0.0006166399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903748,0.003185133,0.001183849,0.002586087,0.0003936936,0.0004405222,0.00003622551,0.00004988522,0.001749787],"genre_scores_gemma":[0.9933164,0.00003828065,0.001908714,0.003159353,0.0003876709,0.00001153314,0.0009068122,0.00002887404,0.0002423617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0368794,"threshold_uncertainty_score":0.9999257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005199566894067345,"score_gpt":0.3099651643346703,"score_spread":0.3047655974406029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}