{"id":"W2048155677","doi":"10.1371/journal.pone.0008868","title":"Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Protein tyrosine phosphatase; Inflammatory bowel disease; STAT3; STAT protein; Inflammation; Colitis; Immunology; Immune system; Biology; Endocrinology; Internal medicine; Molecular biology; Chemistry; Medicine; Signal transduction; Cell biology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005868085,0.00030339,0.0002852642,0.00006261765,0.0001164513,0.00008151349,0.0006817349,0.0002242138,0.00007284819],"category_scores_gemma":[0.0005438392,0.0002635,0.00007565734,0.0002380383,0.000108217,0.00001297846,0.0002131692,0.0004024061,0.00006569237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002617272,"about_ca_system_score_gemma":0.0001189603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001364765,"about_ca_topic_score_gemma":0.003221649,"domain_scores_codex":[0.9978676,0.0001895747,0.0003778265,0.0006492292,0.0003617516,0.0005539666],"domain_scores_gemma":[0.9982459,0.00003042361,0.0001057959,0.001258734,0.0001354738,0.0002236602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005264061,0.001974793,0.002265393,0.00008431112,0.00002574985,0.00002021497,0.00005529479,8.274621e-7,0.9944129,0.0001231905,0.0003142237,0.0001967259],"study_design_scores_gemma":[0.001291547,0.000629008,0.006545967,0.00003546772,0.00003005811,0.000003938771,0.00002256505,0.00001062301,0.9906129,0.00006224526,0.0004244469,0.0003312878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958591,0.0005455897,0.00002394432,0.000507693,0.00003631533,0.002309812,0.000580782,0.00003725371,0.00009950556],"genre_scores_gemma":[0.9952303,0.00001587499,0.002291639,0.0008168963,0.0001863856,0.0006350299,0.0006351929,0.00004833625,0.0001403253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004280574,"threshold_uncertainty_score":0.9999817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01983519108485939,"score_gpt":0.2283727939331744,"score_spread":0.208537602848315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}