{"id":"W2048186818","doi":"10.1016/j.molcel.2011.03.026","title":"The Specificity and Topology of Chromatin Interaction Pathways in Yeast","year":2011,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":251,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Chromatin; Biology; ChIA-PET; Bivalent chromatin; Histone; Genetics; Saccharomyces cerevisiae; Chromatin remodeling; Computational biology; Histone code; Histone-modifying enzymes; Cell biology; Gene; Nucleosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003713051,0.0001657326,0.0003146629,0.0006533341,0.0004604911,0.001299851,0.0003766499,0.0002594228,0.0007009606],"category_scores_gemma":[0.001026757,0.0005000886,0.0002339742,0.0004648084,0.0005494714,0.001074444,0.0004370883,0.0005453325,0.0003847349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003187158,"about_ca_system_score_gemma":0.0002002738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006455656,"about_ca_topic_score_gemma":0.001094431,"domain_scores_codex":[0.9997905,0.00005406137,0.00001869457,0.00005986012,0.00005240133,0.0000244169],"domain_scores_gemma":[0.9990078,0.0005094061,0.0001313255,0.0001442891,0.00007437246,0.0001327993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007198734,0.0000388925,0.005301733,0.0001247876,0.00002533034,0.0001358673,0.0001936663,0.008930443,0.9558076,0.015055,0.0001678573,0.01349908],"study_design_scores_gemma":[0.00007918265,0.000206342,0.05698863,0.0000314696,0.00007385852,0.001199111,0.0003507584,0.08085729,0.8272916,0.0285526,0.004276844,0.0000922656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775702,0.0009396394,0.01871847,0.0001187002,0.000008429828,0.00001109633,0.0002415011,0.0002244339,0.002167534],"genre_scores_gemma":[0.9957885,0.0002832058,0.003173364,0.00001584278,0.000005500322,0.000009949628,0.0002494684,0.00003941009,0.000434823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001299851,"threshold_uncertainty_score":0.002344906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009781080140130578,"score_gpt":0.1974662931064539,"score_spread":0.1876852129663233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}