{"id":"W2048186818","doi":"10.1016/j.molcel.2011.03.026","title":"The Specificity and Topology of Chromatin Interaction Pathways in Yeast","year":2011,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":251,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Chromatin; Biology; ChIA-PET; Bivalent chromatin; Histone; Genetics; Saccharomyces cerevisiae; Chromatin remodeling; Computational biology; Histone code; Histone-modifying enzymes; Cell biology; Gene; Nucleosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001011773,0.00007163262,0.00007453272,0.00001925429,0.00002714119,0.00000623016,0.0001036609,0.00006785179,0.000008831768],"category_scores_gemma":[0.00001252214,0.00006009935,0.00003259852,0.00003147904,0.00007355862,0.000001153125,0.0000840235,0.00005445166,0.000002398965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006694072,"about_ca_system_score_gemma":0.00001600613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004828218,"about_ca_topic_score_gemma":0.00009446976,"domain_scores_codex":[0.9995143,0.0000409701,0.0001532476,0.0001406569,0.00003784275,0.0001130222],"domain_scores_gemma":[0.9996809,0.000004578359,0.00007141399,0.0001996177,0.00002037847,0.00002307108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002657329,0.00004517794,0.0009927745,0.00001140353,0.000007284175,0.000005158473,0.000162274,0.00001536171,0.9966899,0.0007330183,0.00002693955,0.001284159],"study_design_scores_gemma":[0.0003134496,0.0001909107,0.008407813,0.000006130918,0.00000620974,0.00001113673,0.0004303875,0.0005333906,0.9873341,0.000838253,0.001819406,0.00010885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891901,0.0003719337,0.0006872712,0.00001503484,0.00007106608,0.00007869255,0.000004603157,0.000002088026,0.009579198],"genre_scores_gemma":[0.9990378,0.0001520693,0.0006825785,0.00002891407,0.00001286695,0.000004882918,0.00001086196,0.000009408639,0.00006063674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009847669,"threshold_uncertainty_score":0.245078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009781080140130578,"score_gpt":0.1974662931064539,"score_spread":0.1876852129663233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}