{"id":"W2048194629","doi":"10.1021/ja800140g","title":"Site-Specific Prodrug Release Using Visible Light","year":2008,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Photosensitizer; Chemistry; Prodrug; Singlet oxygen; Dioxetane; Photodynamic therapy; Photochemistry; Visible spectrum; Verteporfin; Chlorin; Combinatorial chemistry; Chemiluminescence; Oxygen; Organic chemistry; Optoelectronics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238895,0.0004236058,0.0004029745,0.0001634719,0.0001361869,0.0003408174,0.0002120525,0.0003681252,0.001151271],"category_scores_gemma":[0.0002396638,0.0001744588,0.0002483838,0.000156312,0.0001762641,0.0003650665,0.0002152041,0.0004910897,0.0003470472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003153933,"about_ca_system_score_gemma":0.0002574015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003978139,"about_ca_topic_score_gemma":0.0005968295,"domain_scores_codex":[0.9998239,0.00001897186,0.000019437,0.00005634488,0.00004661955,0.00003487264],"domain_scores_gemma":[0.9999098,0.00002240783,0.00002714537,0.00001661092,0.00001143087,0.00001258766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005573818,0.00001604477,0.00003607183,0.00002822748,0.000002452164,0.00003061167,0.00001165861,0.00009945942,0.9951494,0.0000953602,0.00003966577,0.004435156],"study_design_scores_gemma":[0.00001131778,0.0001419771,0.0001490909,0.000001647491,0.000004120357,0.00005974289,0.000002507528,0.0002568114,0.9986045,0.00001500609,0.0007510264,0.000002321153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9499225,0.002938565,0.04259631,0.0001363381,0.00007015117,0.0002336453,0.0003236456,0.0004490495,0.003329833],"genre_scores_gemma":[0.9848173,0.001114531,0.01011342,0.00004458252,0.00001054347,0.00007443764,0.0002374017,0.00006303328,0.003524701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001151271,"threshold_uncertainty_score":0.003851354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0255833438333588,"score_gpt":0.3066902426373382,"score_spread":0.2811068988039794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}