{"id":"W2048283075","doi":"10.1021/acs.bioconjchem.5b00023","title":"Macrocyclic Cell Penetrating Peptides: A Study of Structure-Penetration Properties","year":2015,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Penetration (warfare); Biophysics; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948167,0.0002497068,0.0002355377,0.0001663223,0.00008015615,0.0001438527,0.00013185,0.0002446985,0.0005164773],"category_scores_gemma":[0.0002328733,0.00009110561,0.0001540252,0.0002245726,0.0001779861,0.0003066688,0.00008717427,0.0002505298,0.0001987747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001854551,"about_ca_system_score_gemma":0.0001131832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004110495,"about_ca_topic_score_gemma":0.0003119629,"domain_scores_codex":[0.9999039,0.00001823271,0.000005497478,0.00002563786,0.00002845966,0.00001825228],"domain_scores_gemma":[0.999863,0.00004983793,0.00003721727,0.000008636631,0.00002296141,0.00001827655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004451885,0.000009101428,0.00009706727,0.00002903842,0.000002173303,0.00002543458,0.00001093277,0.0001589275,0.9984261,0.00004010185,0.00000492708,0.001151708],"study_design_scores_gemma":[0.000006983285,0.0008087928,0.004197767,0.000004010121,0.00001124848,0.0002132758,0.00001279436,0.001223247,0.9922929,0.00003229011,0.001188857,0.000007873234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925404,0.00362085,0.002841961,0.00002725519,0.000004102051,0.00003082444,0.0001105299,0.00001705528,0.0008071073],"genre_scores_gemma":[0.9928029,0.002939811,0.003188317,0.00002768736,0.000007811798,0.00002127016,0.000186888,0.00001116008,0.0008140357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005164773,"threshold_uncertainty_score":0.00172776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0296953528530216,"score_gpt":0.243849789422243,"score_spread":0.2141544365692214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}