{"id":"W2048306321","doi":"10.4161/23723548.2014.964044","title":"Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"SUMO protein; Oxidative stress; Cell biology; Biology; Lysine; Chemistry; Biochemistry; Ubiquitin; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005451597,0.0004921354,0.0008328907,0.0004159074,0.0001597238,0.00003954877,0.0002197898,0.000600307,0.0001748972],"category_scores_gemma":[0.0007237653,0.0005240443,0.000248649,0.0005679535,0.0001806745,0.0001212426,0.0001646838,0.0007065477,0.0006725286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000715575,"about_ca_system_score_gemma":0.0004179865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002740005,"about_ca_topic_score_gemma":0.00008473977,"domain_scores_codex":[0.9960835,0.0008842694,0.000545464,0.001108921,0.0005979023,0.0007799715],"domain_scores_gemma":[0.9971868,0.0001336034,0.0002686249,0.00106367,0.000624042,0.0007232611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008583901,0.0004190295,0.00007739772,0.00003515329,0.0002189198,0.001889876,0.001146197,0.000753472,0.9809099,0.001179562,0.0002468009,0.01226533],"study_design_scores_gemma":[0.002609233,0.004118722,0.0005606231,0.0001074039,0.0003307213,0.0002888787,0.0005136286,0.001464474,0.9558039,0.0002980065,0.03339794,0.0005064176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8966123,0.00008452852,0.08292447,0.002597721,0.000482679,0.0013587,0.00002706658,0.000221596,0.01569096],"genre_scores_gemma":[0.986219,0.00001481537,0.007423243,0.004672297,0.0003178442,0.0000836265,0.0004531971,0.0001539604,0.0006620286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08960671,"threshold_uncertainty_score":0.9997211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087803510897613,"score_gpt":0.2854798101647643,"score_spread":0.2746017750557881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}