{"id":"W2048338931","doi":"10.1089/jir.2012.0154","title":"STAT Activation in Malignancies: Roles in Tumor Progression and in the Generation of Antineoplastic Effects of IFNs","year":2013,"lang":"en","type":"review","venue":"Journal of Interferon & Cytokine Research","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"stat; STAT protein; Cancer research; Transcription factor; Context (archaeology); Cell growth; Activator (genetics); Biology; Cancer; Signal transduction; Tumor progression; Medicine; Cell biology; STAT3; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002526849,0.0002336864,0.001414981,0.002280917,0.00002567153,0.00003557194,0.0002353232,0.0001532339,0.00002969705],"category_scores_gemma":[0.001841095,0.0001346045,0.0001907026,0.0009372476,0.0001186323,0.0002169244,0.00008770599,0.001576517,0.000001669211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002778135,"about_ca_system_score_gemma":0.0005504644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001122064,"about_ca_topic_score_gemma":0.0001037937,"domain_scores_codex":[0.9961231,0.0009011707,0.001654393,0.0002133998,0.0008145642,0.0002934086],"domain_scores_gemma":[0.9966419,0.001552746,0.000913415,0.0002280998,0.0005984972,0.00006536843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001526373,0.002589826,0.00166881,0.05510914,0.0002020841,0.0003981019,0.002649041,0.00005636802,0.4962375,0.00009657329,0.00133335,0.4381328],"study_design_scores_gemma":[0.007626762,0.01999712,0.006422906,0.7270598,0.0004905619,0.001828129,0.002377035,0.001647397,0.1884462,0.00008715901,0.04338585,0.0006310829],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6072894,0.3909522,0.00006419359,0.0001517838,0.0001046561,0.001376684,0.00000663121,0.00000196807,0.00005242516],"genre_scores_gemma":[0.5440922,0.4555168,0.0001062879,0.000006739785,0.0001687166,0.00005933543,0.00001271973,0.00002363187,0.00001364848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6719506,"threshold_uncertainty_score":0.684927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1452288336652633,"score_gpt":0.4461759563989555,"score_spread":0.3009471227336922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}