{"id":"W2048418800","doi":"10.1002/jctb.2653","title":"Bioproduction of <i>cis</i>‐(1S,2R)‐indandiol, a chiral pharmaceutical intermediate, using a solid–liquid two‐phase partitioning bioreactor for enhanced removal of inhibitors","year":2011,"lang":"en","type":"article","venue":"Journal of Chemical Technology & Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Substrate (aquarium); Eutectic system; Bioreactor; Chromatography; Emulsion; Bioproduction; Bioprocess; Pseudomonas putida; Chemical engineering; Biotransformation; Materials science; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003507423,0.0002345973,0.0006232882,0.0005636708,0.00003831165,0.000004006275,0.0004097645,0.0009824007,0.00001272335],"category_scores_gemma":[0.0006443809,0.000213056,0.0003008198,0.0005332746,0.001036392,0.00002397932,0.0001755882,0.0004012653,5.204501e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004528821,"about_ca_system_score_gemma":0.0001155331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001812131,"about_ca_topic_score_gemma":7.342206e-7,"domain_scores_codex":[0.9979883,0.00003045023,0.001127275,0.000369901,0.0001435073,0.0003405984],"domain_scores_gemma":[0.9979124,0.0000159811,0.001138229,0.0003884123,0.0004756309,0.00006933272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001512172,0.0005001768,0.00004387579,0.00005324065,0.0002071159,0.000007011202,0.00004169765,0.000003806977,0.9928882,0.000321031,0.00006011528,0.004361558],"study_design_scores_gemma":[0.002547317,0.002507883,0.000001949046,0.0001024818,0.000183754,0.0005651621,0.0001559937,0.00008370347,0.9921476,0.0006237167,0.0008961174,0.0001843648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762177,0.0008070378,0.02217563,0.0002006279,0.0002874833,0.0002299356,0.00002634208,0.00003117794,0.00002406593],"genre_scores_gemma":[0.9904433,0.0002664823,0.008958554,0.00002763333,0.0002178747,0.00001242862,0.00003696546,0.00003029753,0.000006432787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01422564,"threshold_uncertainty_score":0.8688173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386207688660067,"score_gpt":0.3186185604428218,"score_spread":0.2947564835562211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}