{"id":"W2048418800","doi":"10.1002/jctb.2653","title":"Bioproduction of <i>cis</i>‐(1S,2R)‐indandiol, a chiral pharmaceutical intermediate, using a solid–liquid two‐phase partitioning bioreactor for enhanced removal of inhibitors","year":2011,"lang":"en","type":"article","venue":"Journal of Chemical Technology & Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Substrate (aquarium); Eutectic system; Bioreactor; Chromatography; Emulsion; Bioproduction; Bioprocess; Pseudomonas putida; Chemical engineering; Biotransformation; Materials science; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001523505,0.0006595404,0.00024866,0.0001799437,0.0001025749,0.000424446,0.0002837194,0.000295796,0.0007516515],"category_scores_gemma":[0.0001116726,0.0001401694,0.0003148465,0.0001763872,0.0001544868,0.0002306536,0.0002243406,0.0004490476,0.0004709535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004248533,"about_ca_system_score_gemma":0.0002858775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009633229,"about_ca_topic_score_gemma":0.001168869,"domain_scores_codex":[0.9998585,0.0000218334,0.00001424805,0.00003705672,0.0000371624,0.00003108822],"domain_scores_gemma":[0.9999099,0.00001789345,0.00003094965,0.000009727751,0.00001505273,0.00001651289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002228224,0.000009700942,0.00002032853,0.00001505241,0.000001296435,0.0000117482,0.000003365421,0.00004383917,0.9994306,0.00001355933,0.000006446936,0.0004216858],"study_design_scores_gemma":[0.000001896175,0.00006147361,0.000117467,0.000001258642,0.000002449988,0.00001347374,0.000003109743,0.0002766103,0.9993772,0.000002683081,0.0001411615,0.000001232615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908965,0.0004009428,0.006616518,0.00006338894,0.00001917914,0.00003965667,0.0002476295,0.0001398321,0.001576354],"genre_scores_gemma":[0.9905912,0.0003513521,0.006727381,0.00002603224,0.000006878274,0.00003211595,0.0002876983,0.00003638111,0.001940927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009633229,"threshold_uncertainty_score":0.003082514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386207688660067,"score_gpt":0.3186185604428218,"score_spread":0.2947564835562211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}