{"id":"W2048477468","doi":"10.1097/tp.0000000000000661","title":"Immunoprotection and Functional Improvement of Allogeneic Islets in Diabetic Mice, Using a Stable Indoleamine 2,3-Dioxygenase Producing Scaffold","year":2015,"lang":"en","type":"article","venue":"Transplantation","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Natural Sciences and Engineering Research Council of Canada","funders":"Canadian Institutes of Health Research","keywords":"Islet; FOXP3; Indoleamine 2,3-dioxygenase; Splenocyte; Population; Transplantation; Immune system; Medicine; Streptozotocin; Cancer research; Immunology; Biology; Diabetes mellitus; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009524,0.0003896757,0.0001586141,0.0001976094,0.00006704895,0.0002457656,0.0001306516,0.000181853,0.0003547009],"category_scores_gemma":[0.00005284388,0.00007660012,0.000193843,0.00009297777,0.0001204468,0.0001148696,0.0001048564,0.0002434686,0.00009787161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001012009,"about_ca_system_score_gemma":0.00009963317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001170474,"about_ca_topic_score_gemma":0.0002023222,"domain_scores_codex":[0.9999524,0.000003776613,0.000003926427,0.00001239162,0.00001491583,0.00001258245],"domain_scores_gemma":[0.9999181,0.000006888282,0.00003926268,0.000008063939,0.000005615949,0.00002213409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003476051,0.0000189004,0.00007349184,0.00001032011,0.000001438432,0.00001817289,0.000003606341,0.00003854307,0.9992938,0.00001642441,0.000003656331,0.0004867855],"study_design_scores_gemma":[0.00001232607,0.0003652667,0.002388383,0.000003285772,0.00001774035,0.0001164384,0.000009610013,0.0005742956,0.9959123,0.00001340005,0.0005849157,0.000002111416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962863,0.0004058622,0.002666678,0.0000176681,0.0000166405,0.00001238888,0.00008568569,0.00004584789,0.0004629916],"genre_scores_gemma":[0.9949577,0.0004319311,0.003734742,0.0000174817,0.000007669194,0.00001696525,0.0001600083,0.00001195272,0.0006614365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003896757,"threshold_uncertainty_score":0.001186609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04103400418820548,"score_gpt":0.2458083703462257,"score_spread":0.2047743661580202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}