{"id":"W2048503716","doi":"10.1074/jbc.275.8.5779","title":"Discoidin Domain Receptor 1 Is Activated Independently of β1 Integrin","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"DDR1; Discoidin domain; Collagen receptor; Autophosphorylation; Integrin; Cell biology; Receptor tyrosine kinase; Biology; Tyrosine kinase; Tyrosine phosphorylation; Signal transduction; Receptor; Phosphorylation; Chemistry; Molecular biology; Biochemistry; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001144944,0.0004221747,0.000266758,0.000264663,0.0002112501,0.0004250282,0.0001654712,0.000314277,0.001431709],"category_scores_gemma":[0.0001760191,0.0001755456,0.0002651754,0.0002105409,0.0002545578,0.0001992699,0.0001913226,0.0003567594,0.0006605127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006636224,"about_ca_system_score_gemma":0.0001614697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000477998,"about_ca_topic_score_gemma":0.0008257653,"domain_scores_codex":[0.9998053,0.00003083273,0.00001283154,0.00005298391,0.000039374,0.00005871713],"domain_scores_gemma":[0.9998635,0.00002680302,0.00005865462,0.00001281427,0.000009075378,0.00002919435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000063894,0.000005574132,0.0002294974,0.00003567932,0.000002576235,0.00007880471,0.000008534756,0.00001921459,0.9988563,0.0001160956,0.00004677751,0.0005369025],"study_design_scores_gemma":[0.00003462777,0.0001526534,0.02241616,0.000009068253,0.00001751152,0.001710469,0.00004497079,0.0007105411,0.9666821,0.0001394484,0.008071532,0.00001105876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871911,0.006555596,0.00247841,0.0001775123,0.00003750021,0.00002612779,0.0006528046,0.00007609644,0.00280489],"genre_scores_gemma":[0.9910979,0.002116986,0.001460382,0.00009992816,0.00001761042,0.00003110999,0.001364234,0.00001273843,0.00379917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001431709,"threshold_uncertainty_score":0.004814923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03010686340938822,"score_gpt":0.3090603469835848,"score_spread":0.2789534835741966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}