{"id":"W2048587814","doi":"10.1371/journal.ppat.1004324","title":"RC1339/APRc from Rickettsia conorii Is a Novel Aspartic Protease with Properties of Retropepsin-Like Enzymes","year":2014,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Insect symbiosis and bacterial influences","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"European Regional Development Fund; Fundação para a Ciência e a Tecnologia; Programa Operacional Temático Factores de Competitividade; National Cancer Institute; National Institutes of Health; Stockholms Universitet; National Institute of Allergy and Infectious Diseases; Universidade Nova de Lisboa","keywords":"Rickettsia conorii; Biology; Proteases; Protease; Microbiology; Rickettsia; Intracellular parasite; Gene; Virology; Enzyme; Biochemistry; Spotted fever; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429519,0.0002099015,0.0003400466,0.00001247932,0.000167884,0.00007950878,0.0002585539,0.00009624092,0.000393568],"category_scores_gemma":[0.00007454478,0.00006927532,0.00008856296,0.000203755,0.0001674894,0.0001461801,0.00006263991,0.00009116826,0.0000436339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001400311,"about_ca_system_score_gemma":0.00001682383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008340206,"about_ca_topic_score_gemma":0.0002067147,"domain_scores_codex":[0.9986385,0.00008788105,0.0003113346,0.0003743284,0.0002827636,0.000305197],"domain_scores_gemma":[0.9993392,0.00005959019,0.00019948,0.0001266243,0.000167198,0.000107882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001148891,0.0002317893,0.01883348,0.00001813215,0.00004085447,0.000001195975,0.0002845612,4.12858e-7,0.9792487,0.0001141053,0.00008291221,0.001028975],"study_design_scores_gemma":[0.0003037129,0.0009475286,0.1161639,0.0002059952,0.00008073677,0.000002868809,0.0002409176,0.0001320829,0.8786209,0.00009776656,0.002856837,0.0003467393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983922,0.0001161421,0.000002519598,0.0005250635,0.00008432849,0.0003565534,0.0002200209,0.00005631431,0.0002469206],"genre_scores_gemma":[0.9986187,0.000008819185,0.0003643667,0.0005496411,0.0002831377,0.0000543288,0.00002558433,0.000002636403,0.00009277771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1006278,"threshold_uncertainty_score":0.4309294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03390140191068843,"score_gpt":0.1787119219434733,"score_spread":0.1448105200327849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}