{"id":"W2048594374","doi":"10.1097/01.jto.0000284084.26665.47","title":"P3-108: Correlative genomics in a phase II clinical trial of first-line therapy of erlotinib for clinically selected patients with advanced non-small cell lung cancer","year":2007,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Genome British Columbia; BC Cancer Agency","funders":"","keywords":"Erlotinib; Medicine; Oncology; Internal medicine; Lung cancer; Adenocarcinoma; Population; KRAS; Cancer; Epidermal growth factor receptor; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002187109,0.001161418,0.001858616,0.0003019057,0.0005618246,0.0008866236,0.0007677586,0.001662653,0.003552418],"category_scores_gemma":[0.001473563,0.0004160683,0.00125273,0.0004243987,0.001420371,0.0008730028,0.0003916064,0.003658233,0.0006548966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001159041,"about_ca_system_score_gemma":0.001978466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001488141,"about_ca_topic_score_gemma":0.003440474,"domain_scores_codex":[0.9991627,0.0004287994,0.00002714062,0.0001208698,0.00006117189,0.0001993263],"domain_scores_gemma":[0.9992228,0.0001997158,0.0001141659,0.00008160037,0.00004562505,0.0003362254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7304739,0.06116435,0.01832804,0.0002874188,0.001360451,0.0007719344,0.0003822936,0.004685213,0.06093806,0.0005766574,0.007862641,0.113169],"study_design_scores_gemma":[0.4754318,0.4731061,0.03506681,0.00002346455,0.0008991114,0.0008702565,0.0001423,0.002376796,0.007716758,0.000678602,0.003630911,0.00005720348],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953266,0.0003869034,0.0003366892,0.000870016,0.00005960365,0.0007614505,0.001191434,0.00006183088,0.001005404],"genre_scores_gemma":[0.9917206,0.0004483031,0.001811545,0.0007594975,0.0001065191,0.001467813,0.002650483,0.00004343622,0.0009918665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003552418,"threshold_uncertainty_score":0.01188397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03825366415585448,"score_gpt":0.5004756711090539,"score_spread":0.4622220069531994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}