{"id":"W2048624175","doi":"10.1371/journal.pone.0111580","title":"Nicotine Increases Impulsivity and Decreases Willingness to Exert Cognitive Effort despite Improving Attention in “Slacker” Rats: Insights into Cholinergic Regulation of Cost/Benefit Decision Making","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Impulsivity; Nicotine; Cognition; Cholinergic; Psychology; Oxotremorine; Rivastigmine; Nicotinic agonist; Iowa gambling task; Medicine; Neuroscience; Developmental psychology; Dementia; Internal medicine; Disease; Muscarinic acetylcholine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004036264,0.0002472314,0.0004268852,0.0001519703,0.00009177638,0.00002810809,0.000140854,0.0001684053,0.000005690133],"category_scores_gemma":[0.001214558,0.0002440222,0.00006386431,0.0002633966,0.00007137413,0.00002573752,0.0003035931,0.0001129259,0.000003369643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000430201,"about_ca_system_score_gemma":0.00003909293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002116284,"about_ca_topic_score_gemma":0.0007361396,"domain_scores_codex":[0.9982501,0.00009702612,0.0005229021,0.0005780113,0.0002954002,0.0002566158],"domain_scores_gemma":[0.9988058,0.0001504923,0.0002726947,0.0003102263,0.0003339675,0.0001268497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006450837,0.0008983732,0.1666004,0.0001241545,0.00006269602,1.290576e-7,0.00008730229,0.00008231643,0.7991372,0.00001787988,0.000005286245,0.03233912],"study_design_scores_gemma":[0.00205389,0.0007304469,0.1526353,0.001578889,0.0001620312,0.000003256792,0.00009564326,0.004177681,0.83792,0.0002314257,0.00002300482,0.0003884504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925157,0.000610536,0.00596612,0.00001779411,0.00003518313,0.0007769049,0.00000570664,0.00001855485,0.00005354201],"genre_scores_gemma":[0.9946559,0.0001883465,0.004631676,0.00009527824,0.0001782047,0.00007489915,0.0001168265,0.00003863925,0.00002019662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03878273,"threshold_uncertainty_score":0.9950938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125219215336172,"score_gpt":0.2521414783454189,"score_spread":0.2408892861920572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}