{"id":"W2048641311","doi":"10.1002/cbic.201300724","title":"Molecular Interactions between Thiostrepton and the TipAS Protein from <i>Streptomyces lividans</i>","year":2014,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"University of Waterloo","keywords":"Thiostrepton; Streptomyces; Biology; Bacterial protein; Streptomycetaceae; Computational biology; Actinomycetales; Genetics; Microbiology; Chemistry; Gene; Ribosome; Bacteria; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009004422,0.0002441378,0.0002236679,0.00007626398,0.0001140481,0.0002284147,0.0002134188,0.000154068,0.0006781478],"category_scores_gemma":[0.0001637747,0.00008455344,0.0001699558,0.00009445037,0.0001685955,0.0001000282,0.000143567,0.0002787162,0.0002501112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002851888,"about_ca_system_score_gemma":0.0001078645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006399555,"about_ca_topic_score_gemma":0.0008083139,"domain_scores_codex":[0.9998773,0.00003403871,0.000006306059,0.00002122658,0.00004022377,0.00002088446],"domain_scores_gemma":[0.9998975,0.00003211752,0.00002817267,0.000006847833,0.000009231021,0.00002618322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009863052,0.00001972332,0.0004180828,0.0000254248,0.000008254382,0.00009535097,0.00001450553,0.00008849036,0.9981754,0.00006652129,0.00001317431,0.0009764637],"study_design_scores_gemma":[0.000007002897,0.000203697,0.002131688,0.00000262549,0.000008667519,0.0002007422,0.00002461712,0.0005947484,0.9960461,0.00001850209,0.0007573288,0.000004283795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972941,0.0004446654,0.001325187,0.00002382858,0.00000932115,0.000008556563,0.0000301378,0.00002444375,0.0008398181],"genre_scores_gemma":[0.9983146,0.000139587,0.0009577245,0.00001359475,0.00000270221,0.000003241873,0.00007407913,0.000006190543,0.0004882877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006781478,"threshold_uncertainty_score":0.002268672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007240733030975967,"score_gpt":0.2236934045033085,"score_spread":0.2164526714723325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}