{"id":"W2048641311","doi":"10.1002/cbic.201300724","title":"Molecular Interactions between Thiostrepton and the TipAS Protein from <i>Streptomyces lividans</i>","year":2014,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"University of Waterloo","keywords":"Thiostrepton; Streptomyces; Biology; Bacterial protein; Streptomycetaceae; Computational biology; Actinomycetales; Genetics; Microbiology; Chemistry; Gene; Ribosome; Bacteria; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001953004,0.0001581535,0.0002760603,0.00002703899,0.00008853141,0.0000459554,0.0001099778,0.00008566191,0.0001228022],"category_scores_gemma":[0.0003631552,0.00009325278,0.0000955217,0.000101046,0.0001980907,0.00004777842,0.0000838244,0.0002567761,0.00003635568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001687763,"about_ca_system_score_gemma":0.00001845299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001157103,"about_ca_topic_score_gemma":0.000003102101,"domain_scores_codex":[0.9991388,0.00005068584,0.0001880352,0.0003270429,0.0001298413,0.0001655677],"domain_scores_gemma":[0.9992445,0.000144731,0.00008200553,0.0003778403,0.00006125151,0.00008965066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008781589,0.00002896887,0.0004777838,0.00003676176,0.0000954154,0.000001829979,0.0001438156,2.994391e-8,0.9861552,0.0001909229,0.001260994,0.01152049],"study_design_scores_gemma":[0.0008807607,0.0000338823,0.0007120919,0.000138762,0.000155983,0.000007183258,0.00005167478,0.00001792182,0.9761845,0.0003472666,0.02135406,0.0001159073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795818,0.0005234232,0.00003709709,0.01469112,0.00005585346,0.0003835385,0.00001305768,0.00005930075,0.004654773],"genre_scores_gemma":[0.9972237,0.00001845537,0.0003930646,0.0007807751,0.0004434806,0.000005581292,0.00004544963,0.00001741265,0.001072102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02009307,"threshold_uncertainty_score":0.3802738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007240733030975967,"score_gpt":0.2236934045033085,"score_spread":0.2164526714723325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}