{"id":"W2048692522","doi":"10.1128/jb.185.14.4233-4242.2003","title":"Mechanisms of Activation of Phosphoenolpyruvate Carboxykinase from <i>Escherichia coli</i> by Ca <sup>2+</sup> and of Desensitization by Trypsin","year":2003,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Science Council","keywords":"Biology; Phosphoenolpyruvate carboxykinase; Escherichia coli; Trypsin; Desensitization (medicine); Biochemistry; Enzyme; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002574508,0.0003529936,0.0003019212,0.0001211961,0.0002167025,0.0005505403,0.0005240139,0.0003844203,0.001465361],"category_scores_gemma":[0.0001648221,0.000206645,0.0003980138,0.0001085201,0.0003769578,0.0004174116,0.0003057209,0.000556507,0.0005119721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008398503,"about_ca_system_score_gemma":0.0001902339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008001945,"about_ca_topic_score_gemma":0.0005560327,"domain_scores_codex":[0.9997731,0.00003123349,0.00002015566,0.00003947308,0.00007058701,0.00006551295],"domain_scores_gemma":[0.9998587,0.00002689825,0.00004079189,0.00002437459,0.00002157019,0.0000276501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003400607,0.00003572181,0.0003277119,0.00008417534,0.000005786502,0.0001427199,0.00005329615,0.0002135183,0.9966562,0.0008230673,0.0001140762,0.001203696],"study_design_scores_gemma":[0.00007785502,0.0002719759,0.01190276,0.00001787269,0.0000120142,0.0008981091,0.0001058159,0.00477521,0.9778554,0.0006231272,0.003434799,0.00002503516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891774,0.002822581,0.003402863,0.000270156,0.00002658706,0.00006715389,0.0002039941,0.0001861132,0.003843259],"genre_scores_gemma":[0.9952362,0.0007915908,0.001422145,0.0001469068,0.00000500835,0.00003766044,0.0002972994,0.00002682824,0.00203642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001465361,"threshold_uncertainty_score":0.006093502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004282350951712617,"score_gpt":0.1981554693196059,"score_spread":0.1938731183678933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}