{"id":"W2048705639","doi":"10.1074/jbc.m509157200","title":"Autophagy Controls Salmonella Infection in Response to Damage to the Salmonella-containing Vacuole","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":648,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Directorate for Biological Sciences; Ministero dello Sviluppo Economico; Burroughs Wellcome Fund; University of Toronto; Hospital for Sick Children; Ontario Innovation Trust","keywords":"Salmonella enterica; Intracellular parasite; Biology; Vacuole; Autophagy; Microbiology; Salmonella; Type three secretion system; Intracellular; ATG5; Bacteria; Cell biology; Virulence; Cytoplasm; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009359448,0.0001540654,0.0003869852,0.00006500505,0.00005401882,0.00002360922,0.000151941,0.000168377,0.0001918856],"category_scores_gemma":[0.0005583029,0.00008937347,0.0001769961,0.0002519213,0.00004168504,0.00003240437,0.00004045805,0.000373228,0.00002490331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001421397,"about_ca_system_score_gemma":0.00009240613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003071524,"about_ca_topic_score_gemma":0.000002373862,"domain_scores_codex":[0.9987229,0.0001191331,0.0005228479,0.0001718034,0.0002047852,0.0002585404],"domain_scores_gemma":[0.9990276,0.0002759001,0.0001818537,0.0001955121,0.0001121528,0.0002069887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.009275213,0.0002739483,0.03271919,0.000009734376,0.00004018975,0.0005390501,0.00007216836,0.0004133689,0.9548331,0.000008599949,0.0008985031,0.0009169568],"study_design_scores_gemma":[0.002358726,0.001077023,0.7351943,0.0001169781,0.0000330646,0.0002921212,0.00009363735,0.0000585681,0.250806,0.0002879975,0.009539003,0.0001426128],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956194,0.0004788012,0.000199752,0.002329068,0.00008113174,0.0001944785,0.000004896,0.00002145009,0.001071033],"genre_scores_gemma":[0.997202,0.00003696623,0.0001562916,0.001542967,0.0006357196,0.00001057989,0.000003800474,0.00001054852,0.0004011256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7040271,"threshold_uncertainty_score":0.3644544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01660375230691682,"score_gpt":0.2871616320399662,"score_spread":0.2705578797330494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}