{"id":"W2048706786","doi":"10.1634/stemcells.2004-0371","title":"X‐Inactivation Status Varies in Human Embryonic Stem Cell Lines","year":2005,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Krembil Foundation","keywords":"Biology; Endoderm; Ectoderm; Embryonic stem cell; Epigenetics; Mesoderm; Cell biology; Germ layer; Genetics; X-inactivation; Stem cell; Phenotype; Induced pluripotent stem cell; Karyotype; Cellular differentiation; Dosage compensation; Gene expression; Gene; X chromosome; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002602341,0.0002001052,0.0001871914,0.0001210849,0.00009925535,0.00005281448,0.0002466477,0.0001888604,0.00004350453],"category_scores_gemma":[0.000002714507,0.0001998156,0.00007371011,0.0001720438,0.00006199112,0.00001302589,0.0001594554,0.0001726837,0.0001221754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009441,"about_ca_system_score_gemma":0.0001167779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005057571,"about_ca_topic_score_gemma":0.0001625014,"domain_scores_codex":[0.9983092,0.0001318996,0.0002922139,0.0004582813,0.0002549618,0.0005534657],"domain_scores_gemma":[0.9992457,0.00002301841,0.00009888884,0.0004290066,0.00008558237,0.0001178223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004729298,0.0001252795,0.001066284,0.00007058264,0.00001349214,0.000005545416,0.0001055256,0.0007099758,0.9924511,0.00003873728,0.001723752,0.003642384],"study_design_scores_gemma":[0.0006542344,0.0001552,0.0008196322,0.00001687293,0.000005227412,0.000001928087,0.0001874808,0.000166419,0.910955,0.00000990587,0.08681779,0.0002103522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905586,0.001180297,0.0002219557,0.0001236902,0.000117919,0.0003405483,0.00002088292,0.00002166992,0.007414457],"genre_scores_gemma":[0.9740174,0.0003185238,0.0001564111,0.00007326041,0.0002377708,0.00002865877,0.00006508463,0.00003602903,0.02506687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08509403,"threshold_uncertainty_score":0.8148243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01435849683598149,"score_gpt":0.2637027215185694,"score_spread":0.2493442246825879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}