{"id":"W2048706786","doi":"10.1634/stemcells.2004-0371","title":"X‐Inactivation Status Varies in Human Embryonic Stem Cell Lines","year":2005,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Krembil Foundation","keywords":"Biology; Endoderm; Ectoderm; Embryonic stem cell; Epigenetics; Mesoderm; Cell biology; Germ layer; Genetics; X-inactivation; Stem cell; Phenotype; Induced pluripotent stem cell; Karyotype; Cellular differentiation; Dosage compensation; Gene expression; Gene; X chromosome; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003033888,0.0001345137,0.0001434779,0.0005626187,0.0001544988,0.000466725,0.0001543047,0.0002112719,0.002115291],"category_scores_gemma":[0.0004521977,0.0001532511,0.0001337713,0.0004757818,0.0001531489,0.0001857018,0.0002293287,0.0002760331,0.0009090473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001348802,"about_ca_system_score_gemma":0.0001014541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003534195,"about_ca_topic_score_gemma":0.0003768749,"domain_scores_codex":[0.9997225,0.00004879651,0.00006647575,0.00007037347,0.00006595792,0.00002592236],"domain_scores_gemma":[0.9996858,0.0001125633,0.00005692735,0.00006811447,0.00005064551,0.00002600951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001815256,0.0000276109,0.005265272,0.00004589805,0.00002111567,0.000176145,0.0001743278,0.00007048874,0.9863001,0.0003613754,0.0002178204,0.00715838],"study_design_scores_gemma":[0.00003087188,0.0004502319,0.1307188,0.00003443936,0.00009794835,0.002758653,0.0002851119,0.0004141675,0.8387754,0.0005006868,0.02590529,0.00002830541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842415,0.004537407,0.003141588,0.0000814904,0.00002956762,0.000048496,0.002096663,0.00007553778,0.005747713],"genre_scores_gemma":[0.9801689,0.003681014,0.002603306,0.0001376834,0.0000220909,0.0001004958,0.00733168,0.00004968257,0.005905072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002115291,"threshold_uncertainty_score":0.007076323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01435849683598149,"score_gpt":0.2637027215185694,"score_spread":0.2493442246825879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}