{"id":"W2048713356","doi":"10.1155/jbb/2006/80101","title":"Site‐Directed Mutagenesis to Assess the Binding Capacityof Class S Protein of Staphylococcus aureus Leucotoxins to the Surface of Polymorphonuclear Cells","year":2006,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agence Universitaire de la Francophonie; International Union of Biochemistry and Molecular Biology","keywords":"Threonine; Mutagenesis; Histidine; Staphylococcus aureus; Toxin; Chemistry; Biochemistry; Flow cytometry; Molecular biology; Biology; Amino acid; Mutation; Bacteria; Enzyme; Genetics; Serine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002010484,0.0002142343,0.0003588659,0.0007043856,0.0002235929,0.00007611025,0.001019595,0.0001309935,0.0003439377],"category_scores_gemma":[0.0007879933,0.0001375641,0.0001849123,0.002039755,0.0005868145,0.00007180357,0.0003896558,0.0004339437,0.0001580401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004143597,"about_ca_system_score_gemma":0.0003864211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002944631,"about_ca_topic_score_gemma":0.0006264511,"domain_scores_codex":[0.9957923,0.0003916197,0.0006366547,0.0004396449,0.002120519,0.000619312],"domain_scores_gemma":[0.996771,0.0005586877,0.0002068482,0.0007037179,0.001561673,0.0001980341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006781999,0.0002814764,0.001949132,0.00006742449,0.0001291988,0.00002481669,0.0003399597,0.000217095,0.9535442,0.0006756847,0.04177107,0.0003217532],"study_design_scores_gemma":[0.0005483537,0.0002454841,0.01963353,0.0002447103,0.00001675091,0.000003215952,0.0004514966,0.0002599457,0.9059436,0.00002522956,0.07249086,0.0001368172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842014,0.00005867487,0.000329429,0.009321462,0.0004046657,0.002233539,0.0007716274,0.00004669228,0.002632461],"genre_scores_gemma":[0.9900658,0.000009689797,0.00281196,0.0001196844,0.000382963,0.00008130481,0.00004191746,0.00004799417,0.006438647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04760058,"threshold_uncertainty_score":0.5609701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06251454507073087,"score_gpt":0.3487486140389436,"score_spread":0.2862340689682128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}