{"id":"W2048715361","doi":"10.1074/jbc.m100236200","title":"Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Cell biology; p38 mitogen-activated protein kinases; Biology; Intestinal epithelium; Transcription factor; MAPK/ERK pathway; Cellular differentiation; Protein kinase A; CDX2; Kinase; Homeobox; Epithelium; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819777,0.0002661551,0.0001387722,0.0001930027,0.0001744277,0.0002242536,0.00007018831,0.000129574,0.001095261],"category_scores_gemma":[0.00008154397,0.000125686,0.0001696882,0.0001372515,0.0001638697,0.0001876122,0.0001832107,0.0002494869,0.0003084863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002565027,"about_ca_system_score_gemma":0.0001808621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000570126,"about_ca_topic_score_gemma":0.0006167646,"domain_scores_codex":[0.9998966,0.00001704813,0.000006935145,0.00002035716,0.0000291715,0.00002984384],"domain_scores_gemma":[0.9999591,0.000006219693,0.000008630569,0.000004209631,0.000008002597,0.00001392375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001015595,0.00001535351,0.0003422008,0.00003386354,0.000001746817,0.00007576357,0.00002022146,0.00002293037,0.9980024,0.00006300422,0.00002465333,0.001296185],"study_design_scores_gemma":[0.0000283959,0.0002921555,0.03847354,0.00001007067,0.000009303914,0.0006513358,0.0001454904,0.001186834,0.954357,0.0001606427,0.004680027,0.000005161738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921937,0.002905792,0.002512914,0.0001201104,0.00002245515,0.00002617762,0.0002091495,0.00005943934,0.001950186],"genre_scores_gemma":[0.992699,0.001863376,0.001930051,0.00002496767,0.00001348591,0.00002421907,0.0002665044,0.000005571996,0.003172738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001095261,"threshold_uncertainty_score":0.003664017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02819540603404681,"score_gpt":0.2447483850838395,"score_spread":0.2165529790497926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}