{"id":"W2048750982","doi":"10.1016/j.brainresbull.2012.05.003","title":"Molecular basis of axonal dysfunction and traffic impairments in CMT","year":2012,"lang":"en","type":"review","venue":"Brain Research Bulletin","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Phenotype; Gene; Biology; MFN2; Neuroscience; Disease; Genetics; Loss function; Axoplasmic transport; Pathogenesis; Cell biology; Medicine; Pathology; Immunology; Mitochondrial DNA; mitochondrial fusion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003777218,0.001099073,0.001366927,0.001719329,0.0002300487,0.0007857318,0.0009122647,0.001156904,0.001741972],"category_scores_gemma":[0.000428546,0.0002649495,0.0004432292,0.001605915,0.0005398628,0.00100292,0.0005598005,0.001350707,0.001200603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006547721,"about_ca_system_score_gemma":0.0009737571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00149872,"about_ca_topic_score_gemma":0.002003161,"domain_scores_codex":[0.9999067,0.00001026517,0.00001915462,0.00002244874,0.00002876508,0.00001271887],"domain_scores_gemma":[0.9998428,0.00005942062,0.00003272708,0.000006057597,0.00004356748,0.00001529245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001870472,0.0001002483,0.0005517368,0.0115379,0.0001305026,0.001509183,0.00005240282,0.0007096802,0.006958207,0.003710449,0.02613402,0.9484186],"study_design_scores_gemma":[0.00006553454,0.0001278977,0.004359168,0.003640288,0.0005349617,0.009914761,0.0001514137,0.0003623205,0.003234086,0.006274613,0.9712684,0.00006658109],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002680671,0.9983139,0.0002489116,0.000239393,0.0001402851,0.000004486043,0.00002735309,0.00001008748,0.0007475865],"genre_scores_gemma":[0.001088478,0.9978483,0.0003010299,0.0001023772,0.0001720572,0.000005284544,0.00004588733,0.000001032368,0.0004356605],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001741972,"threshold_uncertainty_score":0.005827487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1863696238994397,"score_gpt":0.4024675906386512,"score_spread":0.2160979667392114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}