{"id":"W2048756941","doi":"10.1158/0008-5472.can-06-4645","title":"Hint1 Inhibits Growth and Activator Protein-1 Activity in Human Colon Cancer Cells","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Environmental Health Sciences; National Natural Science Foundation of China; National Cancer Institute; National Foundation for Cancer Research; T.J. Martell Foundation","keywords":"Transfection; Molecular biology; Cell culture; Activator (genetics); Biology; Cancer cell; Expression vector; Luciferase; Transcription factor; Chemistry; Gene; Cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001363312,0.0005332982,0.0003497522,0.0004112318,0.0001495496,0.0002032482,0.0001744026,0.0001915949,0.001904754],"category_scores_gemma":[0.0001511278,0.0001580897,0.0003143525,0.0003063917,0.0001396048,0.00007974446,0.0001827555,0.0006226582,0.0007150845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003089533,"about_ca_system_score_gemma":0.0003149138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002141139,"about_ca_topic_score_gemma":0.003009388,"domain_scores_codex":[0.9998715,0.00002595806,0.00001256767,0.00001896712,0.00003680335,0.0000341895],"domain_scores_gemma":[0.9999056,0.00002830251,0.00001359122,0.00001365755,0.00001260446,0.00002625652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002475158,0.00006982002,0.000167611,0.0000875109,0.00001006764,0.00004972834,0.00001762176,0.00005892593,0.9967067,0.00004911937,0.0002215381,0.002313831],"study_design_scores_gemma":[0.00009074014,0.001268468,0.006969664,0.00001270347,0.00003079171,0.0004274757,0.0000359121,0.001359791,0.9826193,0.00004484143,0.007133757,0.000006547486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843168,0.008759366,0.002020302,0.0003132633,0.0001043017,0.00008277228,0.001401243,0.0003041776,0.002697712],"genre_scores_gemma":[0.983613,0.004918625,0.002701307,0.0002009287,0.00002736134,0.0001172071,0.003212714,0.00003656173,0.005172326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002141139,"threshold_uncertainty_score":0.006372035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03515904182279395,"score_gpt":0.3636672210574031,"score_spread":0.3285081792346091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}