{"id":"W2048767933","doi":"10.1210/en.2006-0168","title":"Pigment Epithelium-Derived Factor Is Estrogen Sensitive and Inhibits the Growth of Human Ovarian Cancer and Ovarian Surface Epithelial Cells","year":2006,"lang":"en","type":"article","venue":"Endocrinology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Directorate for Biological Sciences","keywords":"PEDF; Endocrinology; Internal medicine; Biology; Estrogen; Ovarian cancer; Cancer research; Cell growth; Ovarian carcinoma; Estrogen receptor; Cancer; Medicine; Angiogenesis; Breast cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000524737,0.0001543209,0.0001703765,0.00002571953,0.0001148879,0.00001383237,0.00007544206,0.00008964786,0.00003123001],"category_scores_gemma":[0.000007300452,0.0001222378,0.0000374839,0.00003685383,0.0002119174,0.000004053228,0.0001053945,0.00007704439,0.000001920578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001064963,"about_ca_system_score_gemma":0.00002660794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001449191,"about_ca_topic_score_gemma":0.0001698756,"domain_scores_codex":[0.9990594,0.0001074058,0.0002014322,0.0003063883,0.00008150434,0.0002438713],"domain_scores_gemma":[0.9995978,0.00002331685,0.000112265,0.0001633525,0.00006328223,0.00003994405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004686152,0.00002751462,0.00530625,0.00001278885,0.00006509769,0.000005769002,0.00028803,0.000004841107,0.9918906,0.00170635,0.0003492252,0.0002966659],"study_design_scores_gemma":[0.0008854178,0.0001788224,0.02648117,0.000005697269,0.0000288274,0.00003057342,0.0001207389,0.00001126789,0.9710162,0.0002905651,0.0008262728,0.0001244215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977383,0.0004443612,0.0002763842,0.0007477282,0.000122273,0.000225727,0.0001623967,0.00000737959,0.0002754559],"genre_scores_gemma":[0.9985969,0.0003388847,0.000275263,0.0003284884,0.0001499293,0.00001073815,0.00004755771,0.00001512738,0.0002370859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02117492,"threshold_uncertainty_score":0.4984711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009841314554849635,"score_gpt":0.24630395327022,"score_spread":0.2364626387153703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}