{"id":"W2048788153","doi":"10.1371/journal.pone.0004884","title":"Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Ontario Genomics Institute; National Institutes of Health; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Pharmaceutical Research and Manufacturers of America Foundation; Wellcome Trust; VINNOVA; Stiftelsen för Strategisk Forskning","keywords":"GTPase; Cell biology; GTPase-activating protein; Effector; Biology; Small GTPase; MAPK/ERK pathway; Signal transduction; Guanine nucleotide exchange factor; G protein","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001316345,0.0005676968,0.0002174698,0.0002261015,0.0001877652,0.0002179969,0.0003191211,0.0004546296,0.001768139],"category_scores_gemma":[0.00009005778,0.00009514696,0.0003471207,0.0002058651,0.0003337503,0.0001128689,0.0002616467,0.0002941486,0.001686174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003421667,"about_ca_system_score_gemma":0.0002527425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002575927,"about_ca_topic_score_gemma":0.0002630946,"domain_scores_codex":[0.9998802,0.00001422075,0.000009419264,0.00003702715,0.00003608772,0.00002305145],"domain_scores_gemma":[0.9999286,0.000005083341,0.00003157687,0.000006718738,0.000008888946,0.0000190875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002192255,0.00002791497,0.0009373731,0.00009563882,0.0000114566,0.0002243466,0.000008487967,0.0001212932,0.9942163,0.0003761666,0.0002566405,0.003505087],"study_design_scores_gemma":[0.00004323348,0.0004246624,0.01035338,0.00001830745,0.00004680185,0.00183617,0.00002504267,0.0009225548,0.9672974,0.0001176172,0.01890568,0.00000915488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982853,0.005617463,0.005004549,0.0002548247,0.0001355909,0.00008930748,0.001140323,0.0004853145,0.004419747],"genre_scores_gemma":[0.9816332,0.002060431,0.005483635,0.0001678189,0.00003811553,0.0000544983,0.002942366,0.00005540851,0.007564397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001768139,"threshold_uncertainty_score":0.005915046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01669418580463134,"score_gpt":0.225752380713863,"score_spread":0.2090581949092317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}