{"id":"W2048800818","doi":"10.1016/s0140-6736(08)60697-2","title":"An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial","year":2008,"lang":"en","type":"article","venue":"The Lancet","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":330,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Québec","funders":"","keywords":"Medicine; Nephrectomy; Renal cell carcinoma; Clinical endpoint; Population; Surgery; Intention-to-treat analysis; Internal medicine; Adjuvant therapy; Kidney cancer; Placebo; Randomized controlled trial; Cancer; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001723218,0.001736478,0.003560429,0.0003627489,0.0003310185,0.0009479948,0.001078625,0.00178783,0.004516708],"category_scores_gemma":[0.001637426,0.0006183208,0.002018876,0.0004322489,0.001504435,0.001132038,0.000462759,0.003650689,0.0008542756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008300898,"about_ca_system_score_gemma":0.001061006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001343174,"about_ca_topic_score_gemma":0.002242882,"domain_scores_codex":[0.9994332,0.00032121,0.00002352752,0.0001000547,0.00003440646,0.00008756421],"domain_scores_gemma":[0.9990844,0.00034239,0.000177963,0.00007894637,0.00003576127,0.0002806716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9827,0.002799086,0.0003068078,0.0004121183,0.0005773334,0.00002424654,0.00004284716,0.0004629834,0.001418032,0.00007470676,0.0003899425,0.01079195],"study_design_scores_gemma":[0.9266179,0.07088954,0.000883147,0.0000249963,0.0003579061,0.00002844023,0.00001932172,0.0004405671,0.0003186637,0.0001335941,0.000273372,0.00001251554],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918419,0.003891735,0.0005220897,0.0006112183,0.0005489773,0.001108351,0.0004374609,0.00008087105,0.0009574298],"genre_scores_gemma":[0.9906961,0.002306759,0.00110203,0.0006890454,0.0003463601,0.001379967,0.0006451473,0.00001937872,0.002815248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004516708,"threshold_uncertainty_score":0.01510996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0778533306348733,"score_gpt":0.3237972363833372,"score_spread":0.2459439057484639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}