{"id":"W2048816591","doi":"10.1074/jbc.m114.630780","title":"A Sorting Signal Suppresses IFITM1 Restriction of Viral Entry","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Infectious Diseases and Mycology","field":"Veterinary","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Retrovirus; Biology; Viral entry; Transmembrane protein; Heptad repeat; Virus; Cell biology; Gene knockdown; Virology; Peptide sequence; Biochemistry; Viral replication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300566,0.0002614245,0.0002028562,0.0001294049,0.0001390564,0.0002353428,0.0001919004,0.000277021,0.0008583692],"category_scores_gemma":[0.0001193503,0.0001099072,0.0002165742,0.00009561137,0.0002066432,0.0001810852,0.0001969941,0.0006077489,0.0002860285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002456724,"about_ca_system_score_gemma":0.0001904375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002695013,"about_ca_topic_score_gemma":0.0003085883,"domain_scores_codex":[0.9998263,0.00002511876,0.0000250913,0.00003969288,0.00004008814,0.00004382449],"domain_scores_gemma":[0.9998265,0.00002766777,0.00006284321,0.00002478766,0.00001385071,0.00004440279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003409192,0.000006691755,0.00005517461,0.000008049089,0.000001067356,0.00001124721,0.000003356285,0.00001179799,0.9996018,0.00003232477,0.000006833636,0.0002276008],"study_design_scores_gemma":[0.000006137742,0.0001124232,0.002198033,0.000002417404,0.00000433784,0.000188938,0.0000113726,0.0005246804,0.9961045,0.00002033792,0.000824875,0.000001926922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998069,0.0004330434,0.0007864866,0.00003864646,0.00001090317,0.000006932497,0.00009688719,0.00004235191,0.0005157103],"genre_scores_gemma":[0.9971237,0.0002173291,0.001289046,0.00003758874,0.0000043118,0.00001352271,0.0003098597,0.00001754347,0.0009871296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008583692,"threshold_uncertainty_score":0.002871513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03175146761709808,"score_gpt":0.2944228743877045,"score_spread":0.2626714067706065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}