{"id":"W2048816591","doi":"10.1074/jbc.m114.630780","title":"A Sorting Signal Suppresses IFITM1 Restriction of Viral Entry","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Infectious Diseases and Mycology","field":"Veterinary","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Retrovirus; Biology; Viral entry; Transmembrane protein; Heptad repeat; Virus; Cell biology; Gene knockdown; Virology; Peptide sequence; Biochemistry; Viral replication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002709328,0.0001026396,0.0002776178,0.00002528399,0.00004742363,0.00001010784,0.0001457948,0.0001955184,0.0007395482],"category_scores_gemma":[0.0004695398,0.00007192173,0.000212792,0.00005929056,0.0000836217,0.00004960623,0.00005498709,0.0002518795,0.000004579152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003159251,"about_ca_system_score_gemma":0.00003711259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005604395,"about_ca_topic_score_gemma":7.558455e-8,"domain_scores_codex":[0.9989989,0.00008244762,0.0005048509,0.0001129418,0.00012061,0.0001802067],"domain_scores_gemma":[0.9988983,0.0002115556,0.0005722705,0.00009159034,0.0001360368,0.00009023344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006969279,0.0002502626,0.02534523,0.00007203795,0.000051281,0.0000701818,0.00001502758,0.000028767,0.9713225,0.00009753327,0.0008443748,0.001205855],"study_design_scores_gemma":[0.003230767,0.008768854,0.1077064,0.0002425159,0.0002445449,0.003869072,0.0004064857,0.0004227046,0.8527201,0.01003033,0.01174901,0.000609176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934239,0.0001654181,0.0003291373,0.00004792516,0.0001287657,0.00002865064,0.000007292645,0.00001579425,0.005853104],"genre_scores_gemma":[0.999024,0.00008352653,0.0001575923,0.0000559671,0.0006358223,0.000001576642,0.000005135281,0.000005489287,0.00003086128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1186024,"threshold_uncertainty_score":0.8097534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03175146761709808,"score_gpt":0.2944228743877045,"score_spread":0.2626714067706065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}