{"id":"W2048842060","doi":"10.1038/gt.2011.53","title":"Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model","year":2011,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; University Health Network; McMaster University; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institutes of Health; Terry Fox Foundation","keywords":"Immune system; Biology; Adenoviridae; Virology; Lentivirus; CD8; Splenocyte; Viral vector; Immunology; Immunotherapy; Spleen; Cytotoxic T cell; Antigen; Genetic enhancement; Virus; Recombinant DNA; In vitro; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000335206,0.000422691,0.0005636973,0.0002603098,0.0002533981,0.00003657363,0.0003723492,0.0002978527,0.001154481],"category_scores_gemma":[0.00003771446,0.0003745155,0.0001391492,0.0001873206,0.000380052,0.0002390463,0.00006794521,0.0004352293,0.00007051807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003778969,"about_ca_system_score_gemma":0.0001130577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003644237,"about_ca_topic_score_gemma":0.00001237248,"domain_scores_codex":[0.997462,0.0007278537,0.0005856231,0.0004947756,0.0000748726,0.0006549046],"domain_scores_gemma":[0.9990715,0.0001986009,0.0001820574,0.0004760119,0.00004060569,0.00003124283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01534178,0.0004406343,0.0004167509,0.000007512456,0.0002297935,0.0000103719,0.003904695,0.000001639395,0.9743109,0.00002439466,0.0001883374,0.005123124],"study_design_scores_gemma":[0.00632619,0.0004239645,0.01167522,0.00005530902,0.0000179744,0.00005366927,0.0001669584,0.00004549654,0.9785181,0.0001521533,0.002118306,0.0004467087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9491861,0.04926338,0.0004198999,0.00005691163,0.0002943484,0.0003893147,0.0001118285,0.0001099354,0.0001682995],"genre_scores_gemma":[0.9916238,0.006045301,0.0001180324,0.0003553284,0.00001517025,0.00006998362,0.00008458109,0.00006928883,0.001618521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04321808,"threshold_uncertainty_score":0.9998707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03011003934911796,"score_gpt":0.242078098936626,"score_spread":0.2119680595875081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}