{"id":"W2048866059","doi":"10.1038/ja.2010.137","title":"Modulation of Salmonella gene expression by subinhibitory concentrations of quinolones","year":2010,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Health Canada","keywords":"SOS response; Salmonella enterica; Repressor lexA; Salmonella; Microbiology; Biology; Gene; Reporter gene; Bioreporter; Regulon; Transcriptional regulation; Gene expression; Genetics; Escherichia coli; Bacteria; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003092586,0.00008483086,0.0001657269,0.00002722495,0.00004014097,0.000005789098,0.0002197496,0.00012376,0.000009099133],"category_scores_gemma":[0.00009643249,0.00005925909,0.00007586697,0.00005243192,0.0002462291,0.000007450765,0.00003755369,0.000126746,5.065309e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003936439,"about_ca_system_score_gemma":0.00006830587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004012749,"about_ca_topic_score_gemma":0.000004396469,"domain_scores_codex":[0.9991472,0.00006875575,0.000447902,0.0000677221,0.0001683958,0.0001000239],"domain_scores_gemma":[0.9987353,0.00003133051,0.0006744174,0.0002579493,0.0002653122,0.00003567662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001284856,0.00007642738,0.01963364,0.0000182086,0.00002822499,4.74933e-7,0.00006325521,0.0001102172,0.9785699,0.0000314421,0.001277354,0.00006242414],"study_design_scores_gemma":[0.0002535117,0.0001932635,0.02325021,0.00004034729,0.00003361766,0.0000270685,0.00009149162,0.00004855443,0.9756933,0.00003460836,0.0002756349,0.00005835851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996367,0.000334713,0.002713096,0.00006149157,0.0003755008,0.00006444703,0.00002051518,0.000001358414,0.00006184018],"genre_scores_gemma":[0.9966607,0.0005586809,0.002502456,0.00001193638,0.000185004,3.44251e-9,0.00001268013,0.0000110999,0.00005743965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003616567,"threshold_uncertainty_score":0.2416516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007038812510966788,"score_gpt":0.2374436234872908,"score_spread":0.230404810976324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}