{"id":"W2048896826","doi":"10.1002/ijc.21264","title":"Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma","year":2005,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Ludwig Institute for Cancer Research","keywords":"Recombinant DNA; Medicine; Metastatic melanoma; Immunization; Melanoma; Intradermal injection; Subcutaneous injection; Virology; Dermatology; Immunology; Cancer research; Internal medicine; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001733654,0.001995829,0.002315568,0.0004260557,0.0004409975,0.0006547063,0.0004854639,0.001201773,0.001653971],"category_scores_gemma":[0.0009540693,0.0005971845,0.0009563417,0.0002770976,0.0009463122,0.0006200387,0.0002801039,0.002355936,0.0005537713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005285751,"about_ca_system_score_gemma":0.001320292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004846536,"about_ca_topic_score_gemma":0.0006975124,"domain_scores_codex":[0.9994398,0.0002941965,0.0000183634,0.00007129497,0.00005372852,0.0001226845],"domain_scores_gemma":[0.9994271,0.0001310553,0.00008987617,0.00005396236,0.0000372925,0.000260763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4965652,0.2191432,0.01774636,0.0007137773,0.0006764807,0.0011427,0.0005969529,0.003828898,0.1508274,0.0003499629,0.002486786,0.1059224],"study_design_scores_gemma":[0.1337596,0.8502349,0.008659799,0.00001514637,0.0001400386,0.0003045705,0.00003907729,0.0007348032,0.004719083,0.0001017666,0.001273371,0.00001780324],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951638,0.001026762,0.0007243744,0.0002243136,0.00007947487,0.00187792,0.0002274635,0.00004981884,0.0006261878],"genre_scores_gemma":[0.9910805,0.0009462647,0.001753981,0.000692579,0.0002190252,0.003110081,0.000678036,0.0000229807,0.00149657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002315568,"threshold_uncertainty_score":0.009168565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005776059434975122,"score_gpt":0.2573526310506405,"score_spread":0.2515765716156654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}