{"id":"W2048902326","doi":"10.1210/endo.141.7.7583","title":"Distribution of Uridine Diphosphate-Glucuronosyltransferase (UGT) Expression and Activity in Cynomolgus Monkey Tissues: Evidence for Differential Expression of Steroid-Conjugating UGT Enzymes in Steroid Target Tissues*","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Medical Council of Canada","funders":"","keywords":"Glucuronidation; Glucuronosyltransferase; Steroid; Chemistry; Hydroxysteroid; Androsterone; Biochemistry; Enzyme; Sulfotransferase; Uridine diphosphate; Microsome; Biology; Internal medicine; Endocrinology; Hormone; Dehydrogenase; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519136,0.0001935609,0.0003081039,0.0007916092,0.0002730294,0.0004892752,0.0000819734,0.0002598741,0.001264899],"category_scores_gemma":[0.0001927144,0.0001721265,0.0002139455,0.0004993953,0.00027687,0.0001643433,0.0001909817,0.0002529424,0.0003756871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002804601,"about_ca_system_score_gemma":0.0002229008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002259392,"about_ca_topic_score_gemma":0.003045243,"domain_scores_codex":[0.9998722,0.00002368361,0.000007724331,0.00004692929,0.00002427336,0.00002514199],"domain_scores_gemma":[0.9998349,0.00003142935,0.00004163696,0.00002536256,0.0000290264,0.00003760345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000279479,0.00001090728,0.009896964,0.00004343793,0.00003508283,0.0001851741,0.00008537238,0.00002702983,0.9844368,0.00009210782,0.00005687324,0.004850828],"study_design_scores_gemma":[0.00003158429,0.0006645662,0.5877641,0.0000278436,0.0002267453,0.003501264,0.0003335736,0.001222309,0.3955972,0.0004648434,0.01013873,0.00002725027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858283,0.00594113,0.00373812,0.0001046034,0.00001421396,0.00002336546,0.000894925,0.00008224037,0.003373132],"genre_scores_gemma":[0.9906582,0.002231169,0.003136572,0.0001039667,0.00001942343,0.00005180111,0.001301156,0.00005006439,0.002447763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002259392,"threshold_uncertainty_score":0.004492462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0831781560007816,"score_gpt":0.4067591959740246,"score_spread":0.323581039973243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}