{"id":"W2048911326","doi":"10.1002/stem.575","title":"Growth Factor Independence 1 Protects Hematopoietic Stem Cells Against Apoptosis but Also Prevents the Development of a Myeloproliferative-Like Disease","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Montreal Clinical Research Institute","funders":"Ministry of Human Resources and Social Security; Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Haematopoiesis; Stem cell; Cell biology; Myeloid; Transcription factor; Cancer research; Transplantation; Bone marrow; Myeloid leukemia; Apoptosis; Immunology; Myeloproliferative Disorders; Genetics; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006752068,0.0005366139,0.0002815424,0.0003837298,0.0001101969,0.0001664698,0.000215247,0.0002371301,0.001743354],"category_scores_gemma":[0.00009206182,0.0001010281,0.000160472,0.0001290712,0.0002178475,0.0001171772,0.0001574466,0.001034364,0.0004577715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001502823,"about_ca_system_score_gemma":0.0001810347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003312436,"about_ca_topic_score_gemma":0.0005334258,"domain_scores_codex":[0.9999328,0.000006863178,0.000005125519,0.00001175153,0.00002376924,0.0000198221],"domain_scores_gemma":[0.9998664,0.00001259501,0.00003293412,0.00001466715,0.000009292614,0.00006416113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006839207,0.000196034,0.0005401484,0.00006516154,0.00001218497,0.00009847857,0.0000115159,0.0001091331,0.9904333,0.0001868496,0.00045653,0.007206675],"study_design_scores_gemma":[0.0002445069,0.002806746,0.01637004,0.000022178,0.000052986,0.001178979,0.0000300505,0.0009778215,0.964457,0.0002300442,0.01361542,0.00001425029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907581,0.003432413,0.001215149,0.0002731126,0.0001036316,0.00004243321,0.001151173,0.0004155377,0.002608478],"genre_scores_gemma":[0.9885554,0.001544758,0.001401949,0.0001496439,0.00004500695,0.00004792345,0.00256756,0.00004732368,0.005640547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001743354,"threshold_uncertainty_score":0.005832076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009998878098362174,"score_gpt":0.2206883388033568,"score_spread":0.2106894607049946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}