{"id":"W2048938969","doi":"10.1212/01.wnl.0000339380.23073.58","title":"4-AMINOPYRIDINE TOXICITY WITH UNINTENTIONAL OVERDOSE IN FOUR PATIENTS WITH MULTIPLE SCLEROSIS","year":2008,"lang":"en","type":"article","venue":"Neurology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"4-Aminopyridine; Multiple sclerosis; Toxicity; Medicine; Drug overdose; Emergency medicine; Anesthesia; Internal medicine; Poison control; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003274104,0.00009977275,0.00008915013,0.00005647481,0.00005993152,0.000003111692,0.00005494849,0.00009888939,0.00003041477],"category_scores_gemma":[0.00002894152,0.00007939166,0.00002330154,0.00009586535,0.00009637965,0.000005098757,0.00003005405,0.00008258714,0.000006130163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006522732,"about_ca_system_score_gemma":0.00002704398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002340446,"about_ca_topic_score_gemma":0.0001651375,"domain_scores_codex":[0.9993266,0.00004680853,0.0001035852,0.0002572791,0.0001085376,0.0001572274],"domain_scores_gemma":[0.9996738,0.00001026777,0.0000492231,0.0001302741,0.00009437505,0.00004206568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002856304,0.0001799655,0.9806383,0.000002863802,0.00001480808,0.000010687,0.00001457894,0.00177335,0.01385959,0.0000252572,0.00041726,0.0002070025],"study_design_scores_gemma":[0.002764964,0.001904241,0.9865349,0.000002824052,0.00000339916,0.0000346481,0.000001698552,0.0006386263,0.005259842,0.000005544856,0.002748999,0.0001003364],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983689,0.000007703566,0.0009081289,0.0002329307,0.000134017,0.0001265348,0.000009490725,0.00001069381,0.0002015889],"genre_scores_gemma":[0.9986389,0.00001344966,0.0001078955,0.0008367741,0.000092504,0.00001435557,0.0001325869,0.00001360841,0.0001499003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008599751,"threshold_uncertainty_score":0.3237498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02005687300310425,"score_gpt":0.1913920723967267,"score_spread":0.1713351993936225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}