{"id":"W2048974591","doi":"10.1038/cr.2011.2","title":"A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response","year":2011,"lang":"en","type":"article","venue":"Cell Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Agence Nationale de la Recherche; Canadian Institutes of Health Research; Health Canada; Canadian Foundation for AIDS Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Biology; Vesicular stomatitis virus; RIG-I; Cell biology; Interferon; Sendai virus; Signal transduction; Kinase; Molecular biology; Virology; Innate immune system; Receptor; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001619457,0.00008174328,0.0001451232,0.0003451315,0.0001016142,0.000007937669,0.0001096796,0.0001216397,0.0003308974],"category_scores_gemma":[0.0002976811,0.00006121395,0.00003539177,0.0003013149,0.0005709901,0.0000927785,0.0001289675,0.000433938,0.00008927456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006071886,"about_ca_system_score_gemma":0.00009950159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004155304,"about_ca_topic_score_gemma":0.0001756929,"domain_scores_codex":[0.997037,0.002172394,0.0002217366,0.000184439,0.00006060179,0.000323843],"domain_scores_gemma":[0.9987853,0.0009299895,0.00004935819,0.000139374,0.00008539589,0.00001061392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01327707,0.0001513389,0.02245172,0.00001261826,0.00001126251,0.000009478071,0.0106029,7.361074e-7,0.9521162,0.00009879297,0.0001443681,0.001123532],"study_design_scores_gemma":[0.00059873,0.0002386327,0.4917178,0.00006164913,0.000002093263,0.0000077238,0.0009036314,0.00001305223,0.5062878,0.00009086011,0.00004208303,0.00003594009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977141,0.0003272963,0.000002866554,0.00008961774,0.00007618174,0.00023298,0.00001417569,0.000003845657,0.001538949],"genre_scores_gemma":[0.9938437,0.00002044632,0.000009675649,0.000008757304,0.000004091473,0.00001972812,0.000006770007,0.000006817309,0.006080041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4692661,"threshold_uncertainty_score":0.3623095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08619522089264033,"score_gpt":0.3221821212348892,"score_spread":0.2359869003422489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}