{"id":"W2048979235","doi":"10.1371/journal.pone.0012622","title":"Kinin B1 Receptor Enhances the Oxidative Stress in a Rat Model of Insulin Resistance: Outcome in Hypertension, Allodynia and Metabolic Complications","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association; Sanofi","keywords":"Internal medicine; Endocrinology; Insulin resistance; Xanthine oxidase; NADPH oxidase; Oxidative stress; Chemistry; Insulin; Apocynin; Superoxide; Medicine; Nitric oxide synthase; Nitric oxide; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003051935,0.001080153,0.0009711162,0.0006033398,0.0002543043,0.0002928734,0.0003047568,0.0005163852,0.002111618],"category_scores_gemma":[0.0001367972,0.0003650546,0.0005219011,0.0003360762,0.0004129876,0.0004140425,0.0003000477,0.001844786,0.0004202416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003281966,"about_ca_system_score_gemma":0.000312248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004368311,"about_ca_topic_score_gemma":0.0007875019,"domain_scores_codex":[0.9997986,0.0000342241,0.00001716068,0.00004033591,0.00004487446,0.0000647416],"domain_scores_gemma":[0.9996287,0.00001995984,0.0001116397,0.00004592433,0.00002789088,0.0001658681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005845168,0.001882787,0.001072145,0.00009735792,0.00004081581,0.0003003873,0.00004138501,0.00009590019,0.9873599,0.00006118495,0.0001112539,0.003091564],"study_design_scores_gemma":[0.0006988799,0.04519231,0.03277015,0.0000382881,0.0002760784,0.001934095,0.0002213102,0.001434184,0.9156294,0.0001490102,0.001614539,0.0000418059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978503,0.0006968741,0.000691278,0.00008340745,0.0000396053,0.00003876377,0.0001436247,0.00006020191,0.0003958564],"genre_scores_gemma":[0.9941276,0.00118192,0.001493092,0.0001042375,0.00003230458,0.0001238477,0.0003912474,0.00001718264,0.002528471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002111618,"threshold_uncertainty_score":0.007064044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05904806635113163,"score_gpt":0.2732672857423887,"score_spread":0.2142192193912571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}