{"id":"W2049044463","doi":"10.1158/1538-7445.am2014-lb-90","title":"Abstract LB-90: Molecular mechanism of TAZ-induced lung tumorigenesis","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Carcinogenesis; Hippo signaling pathway; Biology; Cancer research; Activator (genetics); Cell culture; Cell growth; Cell biology; Nude mouse; Cell; Neoplastic transformation; Gene; Molecular biology; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001150428,0.0004722688,0.0002797932,0.000448524,0.0002978139,0.0005189721,0.0004981075,0.0004143645,0.002684061],"category_scores_gemma":[0.0000863462,0.0001674519,0.0004494486,0.0003072963,0.0003141443,0.0003138458,0.0004313785,0.0009556054,0.001771692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005907586,"about_ca_system_score_gemma":0.0002135935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001000271,"about_ca_topic_score_gemma":0.0005645534,"domain_scores_codex":[0.999841,0.00001487747,0.00000888178,0.00004764225,0.00004477906,0.00004268506],"domain_scores_gemma":[0.9999325,0.00000389465,0.00002365116,0.000008482185,0.000009823154,0.00002166415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001049287,0.00003301172,0.0003161984,0.0000848686,0.000008772205,0.0001392128,0.000007984449,0.00007174644,0.9961123,0.0004868702,0.0002877153,0.002346315],"study_design_scores_gemma":[0.00009790019,0.0002915619,0.0130845,0.00002737841,0.00005796833,0.001151006,0.00005486243,0.003091756,0.967374,0.0005060369,0.01424748,0.00001544429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9423722,0.01762084,0.02170141,0.001260435,0.00023832,0.0002102549,0.003783251,0.001458246,0.01135502],"genre_scores_gemma":[0.9878609,0.002548907,0.001574542,0.0001716149,0.00002606445,0.0000566701,0.002465971,0.00004637062,0.005249016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002684061,"threshold_uncertainty_score":0.008979082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04366336451047736,"score_gpt":0.3689347610638837,"score_spread":0.3252713965534063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}