{"id":"W2049047438","doi":"10.1007/s12272-001-1143-0","title":"The effects of isoimperatorin isolated from Agelicae dahuricae on cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells","year":2008,"lang":"en","type":"article","venue":"Archives of Pharmacal Research","topic":"Plant chemical constituents analysis","field":"Agricultural and Biological Sciences","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cyclooxygenase; Chemistry; Degranulation; Leukotriene C4; Arachidonate 5-lipoxygenase; Lipoxygenase; Prostaglandin D2; Pharmacology; Bone marrow; Prostaglandin; Leukotriene; Biochemistry; Enzyme; Biology; Immunology; Arachidonic acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008043448,0.0003950399,0.0002238752,0.0003061552,0.0001778502,0.0001712176,0.0001698565,0.0001978329,0.001432829],"category_scores_gemma":[0.0001147543,0.0001322809,0.0002352139,0.0002094018,0.0001819152,0.0002711546,0.0001304903,0.0005776676,0.0001909921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009752838,"about_ca_system_score_gemma":0.0001595332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005162829,"about_ca_topic_score_gemma":0.0008069201,"domain_scores_codex":[0.9999514,0.000009008284,0.000004958516,0.00001085556,0.000008012683,0.00001581088],"domain_scores_gemma":[0.9998958,0.00003555568,0.00001505801,0.000009413448,0.00001128578,0.00003291004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001128125,0.00009313878,0.0003565839,0.00005127216,0.00001192058,0.0001019886,0.0000403029,0.00004930564,0.995429,0.00005932746,0.00002738069,0.002651654],"study_design_scores_gemma":[0.00006874917,0.001447446,0.01011344,0.000007172263,0.00007302054,0.0001280712,0.00007184035,0.0001981972,0.9864466,0.00004653683,0.001391524,0.000007216896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966067,0.001797736,0.000375897,0.00004681668,0.00003112468,0.00001424474,0.0001709041,0.00001224253,0.0009442139],"genre_scores_gemma":[0.9965229,0.0009599486,0.0004105342,0.0000400811,0.00002571613,0.00001139867,0.0002918426,0.000004309613,0.001733332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001432829,"threshold_uncertainty_score":0.004793286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02916988468062332,"score_gpt":0.279879548590994,"score_spread":0.2507096639103706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}