{"id":"W2049116607","doi":"10.1089/hum.2010.225","title":"Local Long-Term Expression of Lentivirally Delivered IL-10 in the Lung Attenuates Obliteration of Intrapulmonary Allograft Airways","year":2011,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; University Health Network","funders":"International Society for Heart and Lung Transplantation; International Society for Heart and Lung Transplants","keywords":"Lung transplantation; Lung; Transplantation; Transfection; Cystic fibrosis; Genetic enhancement; Transgene; Medicine; Transduction (biophysics); Luciferase; Green fluorescent protein; Immune system; Cytokine; Viral vector; Pathology; Immunology; Biology; Cancer research; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002773677,0.0004220564,0.0003356893,0.0002293744,0.0001124679,0.0003257167,0.0002524027,0.0003364593,0.0008533904],"category_scores_gemma":[0.00009734691,0.0001704177,0.0002831236,0.0001160053,0.0003748537,0.0003069583,0.0001861864,0.001278876,0.0002856081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002973384,"about_ca_system_score_gemma":0.0003410811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004953395,"about_ca_topic_score_gemma":0.0008686334,"domain_scores_codex":[0.9997941,0.00002641624,0.00001964094,0.00003993015,0.00004251406,0.00007733113],"domain_scores_gemma":[0.9998252,0.00002473433,0.00004764549,0.00001505298,0.00001411935,0.00007329589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001214764,0.0001253867,0.000134415,0.00002976633,0.000003380833,0.00002472931,0.00001462634,0.00003613313,0.9985532,0.00003375876,0.00002431478,0.0008989287],"study_design_scores_gemma":[0.00005353673,0.001904451,0.003161986,0.00001424574,0.00003039869,0.0001595897,0.00004998126,0.001070645,0.9924523,0.00003149478,0.001066737,0.000004535445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952945,0.001328063,0.002383016,0.00008859416,0.0000597166,0.00003858683,0.0001027442,0.0001277337,0.0005769382],"genre_scores_gemma":[0.9945167,0.0007471681,0.001969788,0.00007632855,0.00002071753,0.00005410527,0.0002568156,0.00002272942,0.002335611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008533904,"threshold_uncertainty_score":0.002854884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06107622551578341,"score_gpt":0.3215188174577979,"score_spread":0.2604425919420145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}