{"id":"W2049154906","doi":"10.1002/jcb.23010","title":"Cdk1 is required for the self‐renewal of mouse embryonic stem cells","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Cancer Institute; Capital Normal University","keywords":"Cyclin-dependent kinase 1; Embryonic stem cell; Cell biology; Biology; RNA interference; Stem cell; Cellular differentiation; Embryo; CDX2; Gene expression; Gene; Molecular biology; Cell cycle; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183848,0.0003396358,0.0002878068,0.0003313671,0.0002535141,0.0004712523,0.0002607049,0.0001657952,0.001251549],"category_scores_gemma":[0.0002037902,0.0002499531,0.0001623861,0.0001740252,0.0002495409,0.0002729654,0.0002657003,0.0003913786,0.0007802158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004954953,"about_ca_system_score_gemma":0.0003377557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007922843,"about_ca_topic_score_gemma":0.001016088,"domain_scores_codex":[0.9998804,0.00001104324,0.00001729068,0.00003518771,0.00003273119,0.00002324688],"domain_scores_gemma":[0.9997914,0.00002435664,0.00006631677,0.0000266471,0.00002219995,0.0000691784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008864556,0.00001124085,0.0009078171,0.00006033456,0.000004666433,0.0001275344,0.00001490876,0.00007503368,0.996155,0.0003185176,0.00007918593,0.002157238],"study_design_scores_gemma":[0.0000114715,0.00003617124,0.01370759,0.000007790677,0.00001628625,0.000419086,0.00002116867,0.0007658769,0.9799805,0.000152573,0.004875795,0.000005615097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834609,0.007544951,0.004532777,0.0001688875,0.00005669232,0.00002258967,0.00138567,0.0002432778,0.002584232],"genre_scores_gemma":[0.9927967,0.001714454,0.001506958,0.00003503511,0.00001368546,0.00001762355,0.001139765,0.0000473951,0.002728367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251549,"threshold_uncertainty_score":0.004186869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119633900260411,"score_gpt":0.2519161314643744,"score_spread":0.2407197924617703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}