{"id":"W2049176936","doi":"10.1067/mtc.2001.116207","title":"Cardiac surgery increases the activity of matrix metalloproteinases and nitric oxide synthase in human hearts","year":2001,"lang":"en","type":"article","venue":"Journal of Thoracic and Cardiovascular Surgery","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Heart and Stroke Foundation of Canada","keywords":"Nitric oxide synthase; Nitric oxide; Matrix metalloproteinase; Medicine; Citrulline; Zymography; Cardiopulmonary bypass; Nitric Oxide Synthase Type III; Tissue inhibitor of metalloproteinase; Endothelium; Internal medicine; Enos; Endocrinology; Biochemistry; Arginine; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006182894,0.0002095401,0.001941436,0.0005244344,0.0001126154,0.00003815185,0.00004720941,0.0001164486,0.000006550122],"category_scores_gemma":[0.000568379,0.0001363097,0.002578974,0.0004403919,0.0001540172,0.0002172212,0.00006203241,0.0003275845,2.960306e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003500984,"about_ca_system_score_gemma":0.0001615336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00065028,"about_ca_topic_score_gemma":0.000002714611,"domain_scores_codex":[0.997532,0.0006377199,0.0006847224,0.0002125824,0.0006756574,0.0002572942],"domain_scores_gemma":[0.9979715,0.0009555562,0.0003054487,0.0003827936,0.0002026059,0.0001821486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001600232,0.000463771,0.7239127,0.001263275,0.006365002,0.001486631,0.000101744,0.000400709,0.05686322,0.000008656139,0.0008124802,0.2067216],"study_design_scores_gemma":[0.0003359318,0.00005396759,0.9734555,0.001536579,0.003094245,0.004914979,0.0004155317,0.00006165436,0.01305394,0.00005748564,0.002703523,0.0003166687],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8815092,0.1179306,0.0001154262,0.0001048964,0.00009760696,0.0001894742,0.000006044764,0.000007292407,0.00003942042],"genre_scores_gemma":[0.9801548,0.01942538,0.00009035182,0.00002173121,0.0002551845,0.000005185745,0.000002095244,0.00002407123,0.00002117202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2495428,"threshold_uncertainty_score":0.5558547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02568831608119572,"score_gpt":0.2928950742882231,"score_spread":0.2672067582070274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}